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In vitro effects of rooibos herbal tea (Aspalathus linearis) against methamphetamine on the mouse blood brain barrier
(University of the Western Cape, 2014)Methamphetamine (MA), also known as ‘Tik’, has detrimental short- and long-term psychological and morphological effects on the central nervous system (CNS). The lipophilic nature of MA allows it to cross the blood-brain ... -
In vitro evaluation of Leonotis leonurus to validate its potential as an alternative anti-diabetic drug
(University of the Western Cape, 2022)Africa is a rich source of medicinal plants with South Africa being known as a country with a strong history of traditional healing, which masses a variety of approximately 30 000 flowering plants and accounting for ... -
In vitro investigation of putative interactions between the RING finger domain of Retinoblastoma Binding Protein 6 (RBBP6) and various substrates
(University of the Western Cape, 2015)Retinoblastoma Binding Protein 6 (RBBP6) is a RING finger-containing protein which plays a critical role in the 3'-end processing of mRNA transcripts. It is a constituent of the human pre-mRNA processing complex but also ... -
An in vitro investigation of the effects of camellia sinensis and aspalathus linearis on benign (RPWE 1) and malignant (LNCaP) prostate cell lines
(University of the Western Cape, 2015)The prostate is prone to three pathological processes that include inflammation, benign prostate hyperplasia (BPH) and tumors. According to the center for Disease and Control 1999-2012 report, prostate cancer is the second ... -
In vitro investigation of the ubiquitination and degradation of p53 by Murine Double Minute 2 (MDM2) and Retinoblastoma Binding Protein 6 (RBBP6)
(University of the Western Cape, 2015)P53 is one of the most important tumour suppressor proteins in the body which protects the cell against the tumourigenic effects of DNA damage by initiating processes such as apoptosis, senescence and cell cycle arrest. ... -
In vitro modulatory effects of fermented rooibos extract (Aspalathus linearis) against ethanol-induced effects on the mouse blood-brain barrier
(University of the Western Cape, 2014)Alcohol abuse is a growing crisis within South Africa, with severe health and socio-economic implications. Alcohol compromises the function of the blood-brain barrier (BBB), and thus its ability to regulate the homeostatic ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
(University of Western Cape, 2021)Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ... -
In vitro neuroprotective potential of phyllanthin in MPP+- induced toxicity in SH-SY5Y neuroblastoma cells
(University of the Western Cape, 2023)Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease after Alzheimer’s disease, with an estimated 9 million people projected to be affected worldwide by the year 2030. PD is associated ... -
An In vitro Study of Bacterial Leakage of a Novel Implant Abutment Interface
(University of the Western Cape, 2020)Background: The two-stage implant system has proven to be a successful technique in replacing missing teeth (Nascimento et al., 2008). Nevertheless, the presence of micro-gaps that could entrap microbes at the implant-abutment ... -
An in vitro study of composite repair
(2007)The aim of this study is to investigate the repair bond strength of composite resin following micromechanical and chemical means of retention in improving the repair of composite resin specimens. -
An in vitro study of microleakage and surface microhardness of nanocomposite restorative materials
(University of the Western Cape, 2005)The demand for posterior aesthetic restorations has dramatically increased in recent years. Several new materials have been developed with improved aesthetic, adhesive and mechanical properties. However, microleakage ... -
An in vitro study of post-restorative bleaching: effect on microleakage
(University of the Western Cape, 2010)Aim and Objectives: To assess the effect of bleaching on the marginal integrity of Class V composite resin restorations. To determine the effect of a 6% hydrogen peroxide over the counter and a 38% hydrogen peroxide in-office ... -
An in vitro study of the microleakage of a compomer (polyacid modified resin composite) bonded to enamel and dentine with different bonding systems and the effect of saliva contamination there of.
(Stellenbosch University, 2002)Restorative systems classified as polyacid modified composite resins, or compomers, have appeared on the market. An example of this is Dyract AP. Dyract AP must be used with the Prime & Bond NT bonding system. Prime & ... -
An in vitro study of the properties of GICs with bioactive biomaterial modification
(University of the Western Cape, 2019)The fluoride release and chemical adherence to tooth structure remain the most desirable features of glass ionomer restorative cements (GICs). Although the physical properties for multi-surface restorations are well-defined, ... -
An in vitro study on the immunotoxicity of sewage effluents discharged into the Eerste River-Kuils river water catchment system
(2008)"The aim of the study was to use in vitro human whole blood cultures to screen the water samples collected from the Eerste/Plankenbrug river system for cytotoxicity and inflammatory activity and for the first time investigate ... -
An in vitro study on the immunotoxicity of South African beer
(University of the Western Cape, 2008)Traditionally brewed beers are of cultural and economic importance to many African nations. The presence of mycotoxins in African beer is a topic that needs to be addressed, since most African countries have a climate of ... -
In vivo effects of crinum macowanii on the rat cardiovascular system
(University of the Western Cape, 2007)Crinum macowanii (C. macowanii) (Amaryllidacea) as authenticated by Mr. F. Weitz at the Herbarium, University of the Western cape, is widely used a traditional remedy and is thought to have therapeutic value (Fennell and ... -
In-between: a collection of poems of loss and memory
(University of the Western Cape, 2022)My mini-thesis in Creative Writing aims to explore memory and childhood through the lens of spatial and temporal consciousness. The vehicle for navigating these memories, whether individual or collective, real or surreal, ... -
In-service education and classroom practice: Geography teaching in Namibia
(University of the Western Cape, 2001)After gaining independence in 1990, the Ministry of Education and Culture in Namibia introduced significant educational reforms that were to be implemented by currently serving teachers. As most of these teachers were ... -
In-service female teachers' anxieties about mathematics: a reflective study on mathematics classroom practice at a college of education
(UWC, 1994)The incidence of mathematics anxiety manifesting itself in in-service college students is generally on the increase. Such anxiety does not only affect the mathematical performance of students but also their teaching of the ...