Browsing Magister Pharmaceuticae - MPharm by Author "Mugabo, Pierre"
Now showing items 1-8 of 8
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Adverse effects experienced by patients on first line antiretroviral drugs used at Keetmanshoop Hospital (Namibia).
Mutenda, Nicholus Mbangu (University of the Western Cape, 2015)Adverse effects are a significant factor that determine how long patients will tolerate a given antiretroviral drug regimen. They also influence treatment options, and play an important role in the much needed adherence ... -
Cardiovascular effects of aqueous leaf extract of Leonotis leonurus in Anesthetized rats
Tshambuluka, Noxolo (University of the Western Cape, 2008)The present study was designed to evaluate the hypotensive properties and the mechanisms of action of the aqueous leaf extract of Leonotis leonurus in anesthetized male Wistar rats, using computerized blood pressure ... -
Determination of kanamycin plasma concentrations using LC/MS and pharmacokinetics of kanamycin in patients with multidrug-resistant tuberculosis and in patients with multidrug-resistant tuberculosis co-infected with HIV
Abaniwonda, Ibukunoluwa Mercy (University of the Western Cape, 2012)The aim of the study was to determine firstly, kanamycin plasma concentrations using liquid chromatography coupled with mass spectrometry (LC/MS); secondly, to investigate the PK parameters of kanamycin in patients infected ... -
Effects of the alkaloid present in the ethyl acetate: hexane (1 :4) fraction of Crinum macowanii on the isolated perfused rat heart
Njagi, Angela Gakii (University of the Western Cape, 2004)Crinum macowanii (CM) is used in traditional medicine in the treatment of various diseases including ischemic heart disease, rheumatic fever, cancer and skin diseases. The aqueous extract of CM bulbs was found have a ... -
Ethionamide pharmacokinetics in multidrugresistant tuberculosis patients with and without HIVinfection
Ezeukwu, Ifeoma Patricia (University of the Western Cape, 2017)Many studies have investigated the pharmacokinetics (PK) of anti-tuberculosis drugs in tuberculosis patients. However, currently in South Africa, no studies have been done on ethionamide (ETH) PK in adult MDR-TB patients ... -
Microbiological parameters that influence the treatment outcomes of monodrug and multidrug-resistant tuberculosis
Okonji, Osaretin Christabel (University of the Western Cape, 2017)Previous studies have reported microbiological parameters such as HIV infection, resistance to anti-TB drugs such as fluoroquinolones, resistance to previous treatment with anti-TB drugsand extrapulmonary TB, causing poor ... -
Monitoring lipid and haematological abnormalities in paediatric patients on antiretroviral therapy at a Community Health Centre in the Cape Metropole
Nambatya, Winnie (University of the Western Cape, 2014)South Africa faces a huge Human Immunodeficiency Virus (HIV) burden with more than 400,000 children currently on antiretroviral therapy (ART). Studies on lipid and haematological profile changes in paediatrics are of ... -
Prescribing practice at a tertiary level paediatric hospital in South Africa
Sablay, Hyder (University of the Western Cape, 2014)The objectives of the present study were to describe the type and frequency of prescribing errors and error frequency, to determine the error frequency for different drug classes, to identify potential drug interactions ...