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Identification of a transducin (beta)-like 3 protein as a potential biomarker of prediabetes from rat urine using proteomics
(University of the Western Cape, 2010)
Obesity is a globally increasing disease particularly in developing countries and among children. It is mainly caused by intake of diets high in fat and the lack of physical activity. Obesity is a risk factor for diseases ...
Isolation, expression, purification and characterisation of a novel acetyl xylan esterase from streptomyces species ORS10
(University of the Western Cape, 2012)
Lignocellulosic biomass represents an important renewable resource for biofuels production. Lignocellulosic biomass is comprised of cellulose, hemicellulose and lignin. Lignocellulosics are highly recalcitrant to enzymatic ...
¹Genetic analysis of red pigmentation in ‘bon rouge’ pears (Pyrus communis L.)
(University of Western Cape, 2014)
European pear (Pyrus communis L.) is the third most important fruit in South Africa after citrus and apple. The Agricultural Research Council (ARC) breeding programme seeks to obtain a fully red coloured pear. Sports ...
Proteomic and SNP analysis of the Cadherin 10 type-II (CDH10) gene, in the South African autistic population
(University of the Western Cape, 2013)
Autism or autism spectrum disorder (ASD) is a very diverse neurological disorder that manifests specifically in children and infants between the ages of two to three years of age. An individual suffering is deemed as ...
Identification of biomarkers associated with cervical cancer: a combined in silico and molecular approach
(University of the Western Cape, 2014)
Cervical cancer is the leading cause of cancer mortality among black women in South Africa. It is estimated that this disease kills approximately 8 women in South Africa every day. Cervical cancer is caused by the human ...
Characterisation of a novel soybean candidate glutathione peroxidase/thioredoxin-dependent peroxidase in soybean exposed to osmotic/drought stress
(University of the Western Cape, 2012)
Drought stress is a major contributor to reduced soybean crop yield and quality, this can however be mitigated by the plant’s antioxidant defence mechanisms. One group of antioxidant enzymes that are active in these defence ...
Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa
(University of the Western Cape, 2012)
Campylobacter species are the most common bacteria associated with acute diarrhoea and is responsible for 400 to 500 million reported cases globally. It is not uncommon for 35% to 85% of chicken flocks to be infected with ...
Y-STR profiling of four South African populations using the University of the Western Cape 10 locus set
(University of the Western Cape, 2015)
In this study the 10 Y-specific loci of the University of the Western Cape (DYS710, DYS518 385a/b, DYS644, DYS612, DYS626, DYS504, DYS447, DYS447, and DYS481) were analysed in 492 individuals from South African population ...
The isolation and characterisation of novel natural products from marine bacterial symbionts
(University of the Western Cape, 2015)
Drug-resistant infections are a global health crisis and drastically hinder the treatment options to effectively combat disease. Today, natural products remain an important source of novel drug candidates. Micro-organisms, ...
Evaluation of insertion-deletion polymorphisms with the kit Qiagen Investigator® DIPplex for forensic application in South Africa
(University of the Western Cape, 2015)
Insertion-deletion polymorphisms (indels) have been underutilized in forensic
identification of individuals in comparison with single nucleotide polymorphisms
(SNPs) and short tandem repeat (STRs) systems. The use of ...