Now showing items 1-6 of 6
Deciphering a potential cytoprotective role of novel heat shock responsive proteins using a proteomic approach
(University of the Western Cape, 2011)
Myocardial infarction, commonly known as a heart attack, is a condition where the blood supply to the heart tissue is cut off, starving the tissue from oxygen and nutrient supply, with consequent lethal damage to the heart ...
Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ...
The identification of novel regulatory elements in the promoters of heat shock response genes
(University of the Western Cape, 2010)
The main objective of this study was to investigate promoter sequences of putative HSR genes for the presence of unique regulatory elements and modules that might be involved in the regulation of HSR. In order to achieve ...
Development of nanotechnology-based therapeutic approaches to treat HIV
(University of the Western Cape, 2012)
The rapidly expanding field of nanotechnology has been the focus of many biologists with regard to drug delivery. The ability of nanoparticles to enter cellular compartments makes it possible to explore specific treatment ...
Investigation into the role of DWNN in cell death
(University of the Western Cape, 2004)
Many genes are activated to influence the self-destruction programme of the cell. This programme entails synchronised instigation and implementation of numerous subprograms. The arrival of gene targeting aided in the ...
Screening of natural products and alkylating agents for antineoplastic activity
Apoptosis is a process in which a cell programmes its own death. It is a highly organized physiological mechanism in which injured or damaged cells are destroyed. Apart from physiological stimuli however, exogenous factors ...