Discovery of biomolecules from South African marine sponge symbionts through Metagenomic studies
Mapatha, Matlakala Reginah
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Marine sponges are known to harbour diverse microorganisms which have been proposed to be involved in the synthesis of most of the natural compounds derived from sponges. However, only about 1% of these microorganisms can currently be identified through culturebased approaches, limiting the discovery of novel natural compounds. To overcome this limitation, a metagenomics approach has been introduced for the discovery of natural compounds from symbiotic bacterial metagenomic DNA.