Show simple item record

dc.contributor.advisorTiffin, Nicki
dc.contributor.authorvan Vuuren, Larry Peter
dc.date.accessioned2018-07-30T10:13:09Z
dc.date.available2018-08-31T22:10:06Z
dc.date.issued2016
dc.identifier.urihttp://hdl.handle.net/11394/6122
dc.descriptionPhilosophiae Doctor - PhD (Bioinformatics)
dc.description.abstractSystemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by the production of a wide range of autoantibodies directed against selfantigens. SLE can influence almost any organ system and its appearance and course are highly varied, ranging from remission to disease flare. SLE demonstrates a variety of constitutional symptoms, such as the skin, musculoskeletal and mild hematologic involvement. On the other hand, some patients present with primarily hematologic, renal or neuropsychiatric manifestations.
dc.language.isoen
dc.publisherUniversity of the Western Cape
dc.titleIdentification of coding variants associated with familial systemic lupus erythematosus through whole exome sequencing
dc.rights.holderUniversity of the Western Cape


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record