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dc.contributor.advisorMeyer, Mervin
dc.contributor.advisorMohammed, Ahmed
dc.contributor.authorMbandezi, Yamkela
dc.date.accessioned2019-05-13T08:13:41Z
dc.date.available2019-05-13T08:13:41Z
dc.date.issued2018
dc.identifier.urihttp://hdl.handle.net/11394/6786
dc.description>Magister Scientiae - MScen_US
dc.description.abstractNanotechnology has emerged as a promising field in the quest to address health conditions. Green nanotechnology is a fairly new branch of nanotechnology, which aims to produce and utilize nanomaterials in a way that is safe for living organisms and their environment. Plant extracts are increasingly used in the green synthesis of gold nanoparticles (AuNPs), which involves the reduction of sodium tetrachloroaurate (III) dehydrate by phytochemicals present in the plant extract. It is probable that the green synthesised AuNPs are more biocompatible than chemically synthesised AuNPs as biomolecules of plant origin are involved in the synthesis process. Therefore, this study aimed to explore various water extracts from indigenous South African plants, which included Perlagonium capitatum, Otholobium bracteolatum, Gerbera linnae, Morrella quercifolia, Searsia lucida, Phylica bubescens, Euclea racemosa, Tetragonia fruticosa, and Searsia glauca for their potential to synthesize AuNPs and to investigate their toxicity towards several microorganisms known to cause skin infections. These organisms play a significant role in delaying the healing of wounds. The antimicrobial properties of nanoparticles are increasing exploited in the production of wound treatments.en_US
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.subjectGreen nanotechnologyen_US
dc.subjectGold nanoparticlesen_US
dc.subjectAntibacterial activityen_US
dc.subjectPhytochemicalsen_US
dc.subjectCanceren_US
dc.titleEvaluation of cytotoxic activity of gold nanoparticles naturally synthesised from South African indigenous medicinal plant extractsen_US
dc.rights.holderUniversity of the Western Capeen_US


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