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dc.contributor.advisorOnani, Martin
dc.contributor.advisorMeyer, Mervin
dc.contributor.advisorOkuthe, Emily. G
dc.contributor.authorPhathekile, Bonke
dc.date.accessioned2020-12-10T06:50:40Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/11394/7726
dc.description>Magister Scientiae - MScen_US
dc.description.abstractPeptides are among the main drugs which attract much attention because of their great potential in treating sexually transmitted diseases and other chronic diseases. There has been a major challenge of delivering these drugs in mucosal sites with low pH environment. The aim of this study is to synthesize acidic pH stable peptide loaded chitosan nanoparticles gels that could penetrate mucus layers covering the epithelial cells and kill HIV virus. Chitosan nanoparticles were synthesized by crosslinking method called Ionic gelation with Sodium tripolyphosphateTPP.en_US
dc.language.isoenen_US
dc.publisherUniversity of Western Capeen_US
dc.subjectChitosanen_US
dc.subjectMicrobicidesen_US
dc.subjectTripolyphosphateen_US
dc.subjectPoly acrylic aciden_US
dc.subjectAntimicrobial activityen_US
dc.titleSynthesis of peptide-loaded chitosan nanoparticles for the treatment of sexually transmitted infections (STI’s)en_US
dc.rights.holderUniversity of Western Capeen_US
dc.description.embargo2023


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