Search
Now showing items 1-10 of 14
Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)
Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ...
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ...
The interaction between 6 MV X-rays and p(66)/Be neutrons with spherical gold nanoparticles to induce cellular damage
(University of the Western Cape, 2016)
Despite the advances in therapies such as chemotherapy and radiotherapy, tumours have been shown to be resistant to the treatments. Gold nanoparticles (AuNPs) have been recognized as effective radiosensitizers of low energy ...
Development of a receptor targeted nanotherapy using a proapoptotic peptide
(University of the Western Cape, 2015)
The prevalence of obesity amongst South Africans is alarming, with more than 29% of men and 56% of women considered to be obese. Angiogenesis, a process for development of new blood vessels play a major role in growth and ...
Lithium manganese oxide modified with copper-gold nanocomposite cladding- a potential novel cathode material for spinel type lithium-ion batteries
(University of the Western Cape, 2014)
Spinel lithium manganese oxide (LiMn2O4), for its low cost, easy preparation and nontoxicity, is regarded as a promising cathode material for lithium-ion batteries. However, a key problem prohibiting it from large scale ...
Zirconium-induced physiological and biochemical responses in two genotypes of Brassica napus L.
(University of the Western Cape, 2015)
South Africa is one of two countries responsible for the production of approximately
80% of the world’s Zr. The increase in mining activity has detrimental effects on the
environment, especially crop plants, as more ...
Development of high performance composite lithium ion battery cathode systems with carbon nanotubes functionalised with bimetallic inorganic nanocrystal alloys
(University of Western Cape, 2011)
Lithium ion cathode systems based on composites of lithium iron phosphate (LiFePO₄), iron-cobalt-derivatised carbon nanotubes (FeCo-CNT) and polyaniline (PA) nanomaterials were developed. The FeCo-functionalised CNTs were ...
Synthesis of silver nanoparticles and investigating their antimicrobial effects
(University of the Western Cape, 2015)
Water is essential for life, yet access to safe drinking water is still a major concern worldwide due to waterborne diseases. The current study proposes silver nanoparticles (AgNPs) as an antibacterial agent. Silver ...
Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
(2013)
The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ...
One-Dimensional nanostructured polymeric materials for solar cell applications
(University of the Western Cape, 2010)
This work entails the preparation of various polyanilines with different morphologies and their application in photovoltaic solar cells. Zinc oxide (ZnO) with one-dimensional and flower-like morphology was also prepared ...