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Now showing items 11-20 of 23
Electrochemical immunosensor based on cyclodextrin supramolecular interactions for the detection of human chorionic gonadotropin
(University of the Western Cape, 2012)
Glucose oxidase (GOx) and horseradish peroxidase (HRP) are important enzymes for the development of amperometric enzyme linked immunosensors. The selectivity of each enzyme towards its analyte deepens its importance in ...
Cytochrome P450 2E1/Nickel-Poly(propylene imine) dendrimeric nanobiosensor for pyrazinamide - A first line TB Drug
(University of the Western Cape, 2015)
The tuberculosis (TB) disease to this day remains one of the world’s prominent killerdiseases. Pyrazinamide (PZA) is one of the most commonly prescribed anti- tuberculosis (anti-TB) drugs due to its ability to significantly ...
Protein phosphatase biosensor for the detection of cyanotoxins associated with algal bloom
(2013)
The toxicity of microcystin is associated with the inhibition of serine/threonine protein phosphatases 1 and 2A, which can lead to hepatocyte necrosis and haemorrhage. Analysis of microcystin is most commonly carried out ...
Graphenated polyaniline nanocomposite for the determination of polyaromatic hydrocarbons (pahs) in water
(2013)
The thesis presents a simple, sensitive, low cost and a novel graphenated polyaniline doped tungsten trioxide nanocomposite, as an electrochemical sensor for the detection and quantitative and determination of PAHs, which ...
Liquid-liquid interface ion-transfer amperometric sensors for tenofovir as a model nucleoside/nucleotide anti-retroviral drug
(University of the Western Cape, 2014)
Amperometric sensors for Tenofovir, a model nucleotide/ nucleoside reverse transcriptase inhibitor ARV drug, were studied based on the principle of ion-transfer electrochemistry at the membrane-stabilized oil/ water interface ...
Electrochemical characterization of nanostructured SnO2 and TiO2 for potential application as dielectric materials in sulfonated-polyaniline based supercapacitors
(University of the Western Cape, 2010)
In this research project, nanostructured composites based on Tin dioxide (SnO2) and Titanium dioxide (TiO2) with poly-4-styrene sulfonic acid (PSSA) doped polyaniline (PANI) conducting polymer has been investigated based ...
Polymeric tyrosinase nanobiosensor system for the determination of endocrine disrupting bisphenol A
(University of the Western Cape, 2011)
The main objective of this work was to develop simple and sensitive electrochemical sensors for the detection of bisphenol A. To investigate the electrochemical behavior of BPA on a bare glassy carbon electrode. To apply ...
Polyamic acid-graphene oxide nanocomposite for electrochemical screening of antibiotic residues in water
(University of the Western Cape, 2015)
Pollution of water sources, aquifers and wetland systems caused by industry, agriculture, and municipally treated wastewater is a worldwide problem that contributes to the scarcity of clean and potable water. Rivers, ...
Detection of selective tyrosinase inhibitors from some South African plant extracts of lamiaceae family
(University of the Western Cape, 2016)
Various dermatological disorders, such as formation of black pigmented patches on the surface of the skin arise from the over-activity of tyrosinase enzyme's degenerative action. This enzyme is further implicated in the ...
The preparation of an immunosensor for the detection of microcystins and nodularins by immobilisation of a labelled antibody onto a polymer modified electrode
(University of the Western Cape, 2011)
South African dams and reservoirs are increasingly showing the propensity to support sustained populations of Cyanobacteria (blue green algae). These photosynthetic bacteria occur throughout the world and can rapidly form ...