Browsing by Author "Hiss, Donavon"
Now showing items 1-14 of 14
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Antibacterial activity of some South African plant extracts against streptococcus mutans
Kelani, Madeha Mohammed (University of the Western Cape, 2015)Good oral health has a major influence on the general quality of life and well-being. Several chronic and systemic diseases have been attributed to poor oral health. With the increasing incidence of oral diseases, the ... -
Does Olea africana protect the heart against ischemiareperfusion injury?
Maliza, Asanda (2009)Cardiovascular disease is a major health problem and remains the number one cause of death worldwide. For centuries, medicinal plants have been used in different cultures as medicines for the treatment and control of various ... -
Effect of Eurycoma longifolia (Tongkat Ali) on the prostate cancer cell line LNCaP
Abouhamraa, Hamza (2013)Eurycoma Longfolia Jack, also known as Tongkat Ali (TA) is a tropical plant belonging to the family of Simaroubaceae is widely distributed in South East Asian countries. The extracts of TA have been proven to have ... -
The effect of sunitinib on neuroblastoma and glioblastoma cell growth
Roos, Kelly (University of the Western Cape, 2020)Cancer is a global health catastrophe, with neuroblastoma, the most common solid childhood tumor, and glioblastoma, a deadly brain tumor, being aggressive and unresponsive to current treatment modalities. These tumors are ... -
The effects of doxorubicin loaded chitosan-alginate nanoparticles on SK-N-BE(2) neuroblastoma cells
Rahman, Ziyaad (University of the Western Cape, 2022)Cancer is a life-threatening disease and one of the leading causes of death globally. Cancer was thought to be associated with developed countries only but it is increasingly becoming a major health challenge in developing ... -
Effects of Fucoidan and Chemotherapeutic agent combinations on Malignant and Non-Malignant breast cell lines
Abudabbus, Aisha Ibrahim (University of the Western Cape, 2017)Breast cancer is currently one of the most common malignancies in women. Fucoidan (FUC) is a natural polysaccharide with anticancer properties. Despite a number of in vitro and in vivo studies reporting the efficacy of ... -
The effects of various combinations of different Cdasses of anticancer drugs and tyrosine kinase inhibitors on the human MCF-7 and triple-negative MDA-MB 231 breast carcinoma cell lines
Abrahams, Beynon (University of the Western Cape, 2020)Globally, breast cancer is the most common cancer affecting women and it is predicted that in 2030 about 12 million deaths will occur with approximately 21.7 million new cases [2]. Genetic risk factors as well as race and ... -
An evaluation of cancer biomarkers in normal ovarian epithelial cells and ovarian cancer cell lines
Fruka, Tayra (University of the Western Cape, 2019)Introduction: Globally, there are over 190,000 new reported cases of ovarian cancers per annum. This comprises 3% to 4% of all cancers in women. Ovarian cancer is one of the leading causes of deaths in women. Ovarian cancer ... -
Genomic instability in South African breast cancer patients
Langa, Bridget Cebisile (2013)Breast cancer (BC) is one of the most common malignancies in women. Death results from treatment failure and metastatic disease. Thousands of lives might be saved if it was possible to detect and eliminate occult metastatic ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
Kangwa, Tusekile Sarah (University of Western Cape, 2021)Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ... -
Phenotypic and molecular characteristics of Methicillin-resistant Staphylococcus Aureus isolates from stored patient samples in Misurata hospitals and poultry from commercial markets, Libya
Elakrout, Alhussien Ali (University of the Western Cape, 2019)The emergence of virulent and drug-resistant bacterial strains such as methicillin-resistant Staphylococcus aureus (MRSA) is a global public health burden. The World Health Organization (WHO) has placed MRSA and ... -
Role of Rutin in 1-Mtthyl-4-Phenylpyridinium toxicity: Therapeutic implications for Parkinson's disease
Enogieru, Adaze Bijou (University of the Western Cape, 2018)Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. Although the etiology of PD is not ... -
The effects of selective inhibitors of N-Glycosylation and Endoplasmic Reticulum stress inducers on Neuroblastoma cell proliferation and Apoptosis
Eshiak, Ebtehal Elkamel M. (University of the Western Cape, 2017)Among all childhood cancers diagnosed, neuroblastoma (NB) is the most prevalent during infancy. In patients younger than 15 years, it accounts for more than 7% of malignancies and about 15% of all paediatric mortalities. ... -
The effects of selective inhibitors of n-glycosylation and endoplasmic reticulum stress inducers on the expression of neuroblastoma drug resistance
Husein, Wejdan A.B. Mahmud (University of the Western Cape, 2017)Neuroblastoma (NB) represents 8-10% of all childhood tumours and accounts for approximately 15% of all cancer-related deaths in the paediatric population. Approximately half of newly diagnosed children with this tumour ...