Browsing School of Pharmacy by Title
Now showing items 62-81 of 128
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Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability
(University of the Western Cape, 2016)Background: Zidovudine (AZT) is a very useful drug for the management of Human Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. ... -
Formulation of a nevirapine co-crystal as a liquid dosage form
(University of the Western Cape, 2016)Co-crystals are a solid phase phenomena that could enhance the physicochemical properties of an active pharmaceutical ingredient. A co-crystal has never been incorporated into a liquid dosage form with the assurance of ... -
The formulation, manufacture and evaluation of capsules containing freeze-dried aqueous extracts of Leonotis Leonorus or Mentha Longifolia
(University of the Western Cape, 2006)Leonotis leonorus and Mentha longifolia are two herbs commonly used in South Africa, mostly in oral liquid dosage forms. Several disadvantages are associated with these traditional dosage forms which can perhaps be remedied ... -
Hybrid molecules as inhibitors of the monoamine oxidases and caspase 3 for neurodegenerative disorders
(University of the Western Cape, 2016)Neurodegenerative diseases are multifactorial in nature, and taking the complex nature of these disorders into consideration, multi-target directed ligands may present as better options to treat these disorders than the ... -
The impact an accredited third party assessor will have on the regulator’s response time
(University of the Western Cape, 2014)Globally regulators have been under scrutiny for delays in market application (MA) approvals. The main issue that surfaces in studies related to these delays is a shortage in competent reviewers. The concept of a third ... -
Innovator Medicines Versus Generic Medicine Package Inserts Safety Amendments, the Reality in South Africa
(University of the Western Cape, 2017)Availability of clinically relevant and unbiased medicine information goes a long way in promoting rational use of medicines. The package insert (PI) is one of the sources of information utilised by healthcare professionals ... -
Integrating Complementary and Alternative Medicines into Pharmacy Practice: Identifying challenges in meeting professional responsibilities and training needs
(University of the Western Cape, 2017)Community pharmacies are popular suppliers of complementary and alternative medicines (CAMs) and pharmacists encounter requests from consumers for information on them. The purpose of this study was to assess the extent to ... -
Inter-professional collaboration between general practitioners and community pharmacists: general practitioners’ perspectives
(University of Western Cape, 2012)The global movement towards enhancing inter-professional collaboration in patient care is in light of the increasing potency of drugs and complexity of drug regimens, particularly in the chronically ill where poly-pharmacy ... -
Investigating the Economic Impact of Mandatory Electronic Prescribing Requirements in the United States
(University of the Western Cape, 2017)Technological advancements applied to healthcare may holistically improve the economic burden of prescription medication costs. United States legislative actions requiring utilization of electronic prescribing (e-prescribing) ... -
An investigation into the competency framework required for the responsible pharmacist in the pharmaceutical manufacturing sector in South Africa
(The University of the Western Cape, 2017)The pharmaceutical manufacturing sector operates within a highly regulated environment, with companies accountable to South African statutory bodies. The responsible pharmacist (RP) is responsible for their company’s ... -
An investigation into the medicinal properties of Tulbaghia alliacea phytotherapy
(University of the Western Cape, 2009)The reproductive health of individuals is severely compromised by HIV infection, with candidiasis being the most prevalent oral complication in patients. Although not usually associated with severe morbidity, oropharyngeal ... -
An investigation into the relationship between personality type, as measured by the Keirsey Bates Temperament Sorter, choice of practice setting and job satisfaction of pharmacists who graduated from the University of the Western Cape over the period 1990-2005
(University of the Western Cape, 2006)For the study the Keirsey Bates Temperament Sorter was completed by 602 pharmacy students during their study period at the University of the Western Cape. The results showed that the pharmacy students had a tendency towards ... -
Investigation of factors influencing pharmaceutical services and their relation to quality pharmaceutical service delivery in hospitals of a private health care provider group
(2009)Efforts to improve the quality of service delivery are an ongoing feature in different organisations. In the private health care sector, particularly pharmaceutical services in private hospitals, such efforts are important ... -
Investigation of the antidiabetic activity of Cnicusbenedictus L. in rats
(University of the Western Cape, 2016)Diabetes Mellitus, one of the major diseases affecting human population all over the world has caused significant morbidity and mortality. The management of this condition has raised the demand of safe and cost effective ... -
Investigation of the in vitro bioavailability of luteolin from modified preparations of Artemisia afra
(University of the Western Cape, 2014)Artemisia afra (A. afra) is traditionally used for a variety of ailments and contain flavonoids e.g. luteolin which may contribute to some of its activity. It is generally administered as a tea or decoction, and such liquid ... -
Is paracetamol being prescribed and used at the correct therapeutic dose in the children population in South Africa?
(University of the Western Cape, 2014)When used at the recommended and approved therapeutic dose, paracetamol is effective. Paracetamol is available in various forms and easily accessible from general dealers and pharmacies. The liquid form is the preferred ... -
Isolation and Bioassay evaluation of Angiotensin Converting Enzyme inhibitory compounds of Centella asiatica
(University of the Western Cape, 2019)Hypertension is by far the most common risk factor for cardiovascular disease (CVD), which has been identified as the leading cause of death worldwide and a major economic burden in developing countries. Over the years, ... -
Knowledge, perceptions and practices of risk-based monitoring among clinical practitioners in the United States
(University of the Western Cape, 2018)This study investigated the current knowledge, perceptions, and practices of Risk-Based Monitoring (RBM) using written and verbal responses to an ethics review board approved questionnaire. Responses were collected from ... -
Knowledge-based integration of Zimbabwean traditional medicines into the National Healthcare System: A case study of prostate cancer
(University of the Western Cape, 2017)This study sought to identify the bottlenecks in the promotion of Zimbabwean Traditional Medicines (ZTMs) towards improving the national healthcare delivery system. The indigenous medicines lost value and recognition to ... -
A literature review on pharmacovigilance systems in off-label use of medicines
(University of the Western Cape, 2015)Problem and significance: Off-label use of medicines is not illegal; however, it can be risky and harmful, or beneficial and innovative. The main problem of this practice is the lack of systems for monitoring adverse drug ...
