Browsing Magister Pharmaceuticae - MPharm by Author "Joubert, J"
Now showing items 1-2 of 2
-
Synthesis and evaluation of fluorescently linked polycyclic cage derivatives for application in neurodegenerative disorders
Fourie, Locarno Lawrence (University of the Western Cape, 2020)Neurodegenerative diseases (ND) are chronic and progressive in nature, and characterized by the gradual loss of neurons in various regions of the central nervous system (CNS). ND include Alzheimer's disease (AD), Parkinson's ... -
Tacrine, trolox and tryptoline as lead compounds for the design and synthesis of multi-target drugs for Alzheimer's disease therapy
Teponnou, Gerard A. Kenfack (University of the Western Cape, 2016)The cascade of neurotoxic events involved in the pathogenesis of Alzheimer's disease may explain the inefficacy of currently available treatment based on acetylcholinesterase inhibitors (AChEI - donepezil, galantamine, ...