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Stability of freeze-dried aqueous and other modified extracts of Leonotis leonurus
(University of the Western Cape, 2017)
Leonotis leonurus, a South African indigenous medicinal plant, is frequently used in the form of a tea. However, this dosage form has many disadvantages. Consequently three L. leonurus solid extract preparations were ...
Paving a way to effectively regulate African traditional medicines in South Africa
(University of the Western Cape, 2017)
BACKGROUND:
Following the historical suppression of traditional medicines in South Africa, the
government published their National Health Plan in 1994 which made provision for
traditional healing as an integral and ...
Traditional, complementary and alternative medicine in Botswana: patients’ attitudes, knowledge and use
(University of the Western Cape, 2017)
BACKGROUND:
The purpose of this study was to determine use, knowledge and attitudes towards
traditional, complementary and alternative medicine (TCAM) in Botswana among people
who visit public health facilities.
PRIMARY ...
Design, Synthesis and Evaluation of Indole Derivatives as Multifunctional Agents against Alzheimer's disease.
(University of the Western Cape, 2017)
Alzheimer's disease (AD) is an age related neurodegenerative disorder characterised by
progressive memory loss and cognitive impairment. It is one of several
neurodegenerative disorders occurring as a result of a process ...
Polycyclic compounds as carriers for neuroactive non- steroidal anti-inflammatory drugs
(University of the Western Cape, 2017)
Recent scientific findings have highlighted the beneficial roles of polycyclic cage compounds in neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Further interest into the chemistry of these compounds ...
Analysis on access to antiretroviral therapy for patients with different income and educational level, and the effect of treatment on quality of life after two to three months of therapy
(University of the Western cape, 2017)
Access to antiretroviral therapy (ART) for HIV positive patients has brought
hope and a chance to a healthier longer life with improved quality of life (QoL). In this study we
explored the difference in health related ...
Polymer Coating of an Optimized Nano Lipid Carrier System of Harpagophytum Procumbens Extract for Oral Delivery
(University of the Western Cape, 2017)
Harpagophytum procumbens is a traditional medicinal plant widely used in South African
traditional healthcare to treat a range of ailments like degenerative rheumatoid arthritis,
osteoarthritis, tendonitis, kidney inflammation, ...
Ethionamide pharmacokinetics in multidrugresistant tuberculosis patients with and without HIVinfection
(University of the Western Cape, 2017)
Many studies have investigated the pharmacokinetics (PK) of anti-tuberculosis drugs
in tuberculosis patients. However, currently in South Africa, no studies have been
done on ethionamide (ETH) PK in adult MDR-TB patients ...
Preparation, characterisation and evaluation of Artemisia afra phytosomes with modified release properties
(University of the Western Cape, 2017)
Dissolution studies on various dosage forms (powder, tablets, teabags and alginate beads) of
the Artemisia afra freeze dried aqueous extract (FDAE) all exhibit a rapid release profile.
Generally, such a release profile may ...
Development of a model to predict the cost of treatment of breast cancer with chemotherapy at Groote Schuur hospital
(University of the Western Cape, 2017)
In South Africa, breast cancer dominates other forms of cancer affecting women in
both prevalence and mortality rates according to the National Cancer Registry. The
incidence and cost of breast cancer have been on the rise ...