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Electrochemical dynamics of cytochrome P450-3A4 isoenzyme biosensor for protease inhibitor antiretroviral drug
(2010)
This thesis firstly reports on the development and characterization of reagent-less and cobalt(III) sepulchrate[Co(Sep)³⁺] mediated biosensor platforms (biosensor platform 1 and biosensor platform 2), with human recombinant ...
Evaluation of the leachate chemistry and contaminants attenuation in acid mine drainage by fly ash and its derivatives
(University of the Western Cape, 2006)
The mining industry in South Africa has a huge potential to impact negatively on the environment. Negative impacts include generation of reactive tailings and acid mine drainage (AMD). AMD is highly acidic (pH 2-4), ...
The synthesis and evaluation of potential anti-Mycobacterium tuberculosis and apoptotic agents
(University of the Western Cape, 2007)
Tuberculosis (TB) and Cancer are among the most devastating and therapeutically challenging diseases that need to be addressed in South Africa today. The development of muti-drug resistance in TB causing bacteria, Mycobacterium ...
Chemical isolation and electro-chemical characterization of antidiabetic compounds from selected South African lamiaceae plant species
(University of the Western Cape, 2020)
Diabetes mellitus (DM), being one of the most common metabolic disorders with an elevated morbidity and mortality rate around the world. It is characterised by deficiency in insulin secretion or degradation of secreted ...
Phytochemical and biological studies of extracts from selected South African indigenous medicinal plants: Bulbine and helichrysum species
(University of the Western Cape, 2022)
Medicinal plants from the Asteraceae and Asphodelaceae families are among the most widely recognized in South African traditional medicine for managing diabetes mellitus. Diabetes mellitus is a universal epidemic, yet there ...
Phytochemical studies on extracts of selected South African indigenous medicinal plants
(University of the Western Cape, 2022)
Nature has been identified as a rich source of potentially useful chemicals. Throughout the years, phytochemical studies have led to the unearthing of a huge number of natural products, their chemical diversity is unique ...