| dc.contributor.advisor | Onani, Martin O. | |
| dc.contributor.author | Busa, Asanda V. | |
| dc.date.accessioned | 2018-02-14T09:24:58Z | |
| dc.date.available | 2018-04-30T22:10:06Z | |
| dc.date.issued | 2016 | |
| dc.identifier.uri | http://hdl.handle.net/11394/5711 | |
| dc.description | Philosophiae Doctor - PhD (Chemistry) | |
| dc.description.abstract | Malaria remains a major global health problem and to date, hundreds of thousands of people
die as a result of this disease every year. Malaria has been able to adapt and rebound despite
various efforts made to combat the disease. The decrease in efficacy of many front-line drugs
against malaria, due to increased resistance, prompts investigation into obtaining effective
compounds that are able to overcome this resistance. This study investigated the synthesis,
characterisation and biological evaluation of new quinoline (as antimalarial agents) as well as
non-quinoline (as antitumor agents) based compounds. | |
| dc.language.iso | en | |
| dc.publisher | University of the Western Cape | |
| dc.title | Synthesis, characterization, and molecular docking of novel 4-Aminoquinolines and Salicylaldimine complexes: evaluation as antimalarial and antitumor agents | |
| dc.rights.holder | University of the Western Cape | |
