Browsing Faculty of Natural Science by Subject "Obesity"
Now showing items 1-9 of 9
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Development of a receptor targeted nanotherapy using a proapoptotic peptide
(University of the Western Cape, 2015)The prevalence of obesity amongst South Africans is alarming, with more than 29% of men and 56% of women considered to be obese. Angiogenesis, a process for development of new blood vessels play a major role in growth and ... -
Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ... -
The effect of insulin, leptin and inflammatory cytokines on reproductive health and hypogonadism in males diagnosed with the metabolic syndrome
(2013)The metabolic syndrome (MetS) is a collection of various metabolic, hormonal and immunological risk factors that cluster together, closely related to poorly understood phenomena such a hyperinsulinaemia (insulin resistance), ... -
The effect of nigella sativa oil on male reproductive function in male Wistar rats exposed to an obesogenic diet
(University of Western Cape, 2020)Obesity is a growing public health concern globally, particularly in developed countries such as the United States (US). More than 30% of Americans are considered obese. In the past 20 years in America, incidence of ... -
Evaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening models
(University of the Western Cape, 2014)The aim of this study was therefore to evaluate the antioxidant and anti-diabesity potential of a hot water extract of C. maculata in non-cell based assays and correlate the activities with phenolic composition. Total ... -
Identification of a transducin (beta)-like 3 protein as a potential biomarker of prediabetes from rat urine using proteomics
(University of the Western Cape, 2010)Obesity is a globally increasing disease particularly in developing countries and among children. It is mainly caused by intake of diets high in fat and the lack of physical activity. Obesity is a risk factor for diseases ... -
Identification of sub-clinical biomarkers that predict the risk of developing diabetic cardiomyopathy
(University of the Western Cape, 2022)Cardiovascular disease (CVD) is the leading cause of death of people with obesity and type 2 diabetes (T2DM). According to a statistical report from the World Health Organization (WHO), approximately 17.9 million people ... -
Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
(University of the Western Cape, 2023)The incidence and prevalence of obesity and its related diseases has nearly tripled and is increasing at an alarming rate worldwide. Several modern methods for the management and treatment of obesity are available, with ... -
Isolation and characterization of natural products from selected Rhus species
(University of Western Cape, 2020)Searsia is the more recent name for the genus (Rhus) that contains over 250 individual species of flowering plants in the family Anacardiaceae. Research conducted on Searsia extracts to date indicates a promising potential ...