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The association between environmental exposures during childhood and the subsequent development of crohn's disease in the Western Cape
(University of the Western Cape, 2015)
Background: A subtype of inflammatory bowel disease, Crohn’s disease is thought to represent a complex interaction between environmental factors, a defective immune system, the gastrointestinal microbiome and genetic ...
Ursolic acid and oleanolic acid as novel therapeutic agents in breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the most common cancers among women in South Africa and the second leading cause of cancer death after lung cancer. According to the American Cancer Society 2015, women have a 12% chance of developing ...
The effects of Ethanol and Aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)
The blood brain barrier (BBB) is a signaling interface between the blood and the central nervous system (CNS), which prohibits the entry of harmful blood-borne substances into the brain micro-environment, thus maintaining ...
The possible effect of Hypoxis hemerocalledia (African potato) on blood glucose levels : an in vitro study
(University of the Western Cape, 2015)
The plant Hypoxis hemerocallidea, also known as the African potato, is commonly
used as a traditional medicine to treat diabetes in South Africa. The mechanism by
which it lowers blood glucose levels is not known. The ...
Comparative in vitro study of the anti-cancer effect of apricot and peach kernel extracts on human colon cancer cells
(University of the Western Cape, 2015)
Amygdalin, a controversial anti-cancer agent, is a cyanogenic glycoside plant compound found in apricot and peach kernels. Both amygdalin and its patented form, Laetrile®, have been promoted and sold as "vitamin B-17", ...
Comparison between chemical and tissue culture methods to monitor environmental estrogens
(University of the Western Cape, 2012)
Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ...
Antibacterial activity of some South African plant extracts against streptococcus mutans
(University of the Western Cape, 2015)
Good oral health has a major influence on the general quality of life and well-being. Several chronic and systemic diseases have been attributed to poor oral health. With the increasing incidence of oral diseases, the ...
The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
(University of the Western Cape, 2014)
The aim of the study was to detect the prevalence of AV and its associated bacteria with preterm delivery in the Western Cape, South Africa. Furthermore, it sought particularly to examine and investigate the predictive ...
The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)
The blood brain barrier (BBB) is a signaling interface between the blood and the
central nervous system (CNS), which prohibits the entry of harmful blood-borne
substances into the brain micro-environment, thus maintaining ...
Modulation of colon carcinogenesis by dietary ω-6/ω-3 fatty acid ratios : a chemopreventive strategy?
(University of the Western Cape, 2015)
The aim of this study was to determine whether dietary fats constituting specific ω-6/ω-3 fatty acids (FA) ratio has chemopreventive modulating effects on the development of colon cancer. Western diets intake of saturated ...