Browsing Magister Scientiae - MSc (Medical BioSciences) by Author "Ekpo, Okobi"
Now showing items 1-7 of 7
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Evaluating the neuroprotective effects of fermented rooibos herbal tea in Wistar rats exposed to bisphenol-A during gestation and lactation
Gamoudi, Bushra Khalifa (University of the Western Cape, 2019)Exposure to endocrine-disrupting chemicals as bisphenol A (BPA) during gestation and early postnatal life is known to disrupt normal developmental processes and alter the body’s endocrine system leading to deleterious ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
Kangwa, Tusekile Sarah (University of Western Cape, 2021)Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ... -
In vitro neuroprotective potential of phyllanthin in MPP+- induced toxicity in SH-SY5Y neuroblastoma cells
Delport, Joshua (University of the Western Cape, 2023)Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease after Alzheimer’s disease, with an estimated 9 million people projected to be affected worldwide by the year 2030. PD is associated ... -
Liposomal drug delivery to brain cancer cells
Boltman, Taahirah (University of the Western Cape, 2015)Neuroblastomas (NBs) are the most common solid extra-cranial tumours diagnosed in childhood and characterized by a high risk of tumour relapse. Like in other tumour types, there are major concerns about the specificity and ... -
The potential neuroprotective effects of two South African plant extracts in hydrogen peroxide-induced neuronal toxicity
Gier, Megan Loran (University of the Western Cape, 2018)Background: Oxidative stress induced by reactive oxygen species has been strongly associated with many neurodegenerative diseases (NDDs) and many medicinal plant-derived products have been reported to exert potent antioxidant ... -
Radioprotective effects of rooibos herbal tea on the developing central nervous system of wistar rats
Alrtemi, Milod M Ahmed (University of the Western Cape, 2018)Background: Early postnatal radiation exposure from environmental, diagnostic or therapeutic sources is potentially deleterious to the developing nervous system resulting in oxidative stress, structural damage, altered ... -
The effects of selective inhibitors of n-glycosylation and endoplasmic reticulum stress inducers on the expression of neuroblastoma drug resistance
Husein, Wejdan A.B. Mahmud (University of the Western Cape, 2017)Neuroblastoma (NB) represents 8-10% of all childhood tumours and accounts for approximately 15% of all cancer-related deaths in the paediatric population. Approximately half of newly diagnosed children with this tumour ...