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Aptamer selection against GFRa1 for its application in the prognosis of breast cancer
(University of the Western Cape, 2019)
Breast cancer is the second most common cancer amongst South African women. Despite
ongoing efforts to combat breast cancer, current prognostic and/or therapeutic monitoring
methods are limited since very little improvement, ...
The identification of aptamers against serum biomarkers of human tuberculosis
(University of the Western Cape, 2018)
Tuberculosis (TB) is a global health problem and rated as the second leading cause of death after HIV/AIDS. Transmission of TB from one person to the next is very rapid in crowded communities. Therefore, it is crucial to ...
Development of an aptamer based lateral flow test strip for a diabetes biomarker
(University of the Western Cape, 2019)
Diabetes mellitus is one of the major chronic diseases that poses a significant risk to human
health globally. Current diagnostics for diabetes are based on blood glucose measurements,
which can go unnoticed for years. ...
Targeted delivery of GFP loaded polymeric nanoparticles to CD4 expressing cells using a CD4 specific aptamer
(University of the Western Cape, 2020)
Human Immunodeficiency Virus (HIV), which is the cause of Acquired Immunodefiency Syndrome (AIDS) is a major global public health issue affecting over 37 million people worldwide and is responsible for claiming over 32 ...