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Now showing items 11-20 of 78
An investigation of the zinc binding characteristics of the RING finger domain from the human RBBP6 protein using heteronuclear NMR spectroscopy.
(University of the Western Cape, 2007)
Retinoblastoma binding prot
ein 6 (RBBP6) is a 250 kDa human splicing-associated
protein that is also known to
interact with tumour suppresso
r proteins p53 and pRb and to
mediate ubiquitination of p53 via its ...
Sample preparation methods and molecular based detection for the rapid isolation and identification of Listeria monocytogenes in food samples
(University of the Western Cape, 2006)
Listeria monocytogenes is a Gram-positive bacterium responsible for listeriosis, a food-borne disease, which may result in severe illness and possible death. The importance of L. monocytogenes as a food-borne pathogen has ...
Investigation into the role of DWNN in cell death
(University of the Western Cape, 2004)
Many genes are activated to influence the self-destruction programme of the cell. This programme entails synchronised instigation and implementation of numerous subprograms. The arrival of gene targeting aided in the ...
The genease activity of mung bean nuclease: fact or fiction?
(University of the Western Cape, 2004)
The action of Mung Bean Nuclease (MBN) on DNA makes it possible to clone intact gene fragments from genes of the malaria parasite, Plasmodium. This “genease” activity has provided a foundation for further ...
Studies on the population genetics of Euphausiids: a comparison of patterns in plagic taxa displaying different distributions and life-histories
(University of the Western Cape, 2006)
The systematic and population genetic relationships were characterised for three ecologically related euphausiid species: Euphausia lucens, E. recurva and E. vallentini. These species have different geographical distributions ...
Transcription regulation and candidate diagnostic markers of esophageal cancer
(University of the Western Cape, 2009)
Esophageal cancer (EC) ranks among the ten most frequent cancers worldwide. Mortality rates associated with EC are very similar to the incidence rates due to the relatively late stage of diagnosis and the poor efficacy of ...
Comparison of actinobacterial diversity in Marion Island terrestrial habitats
(University of the Western Cape, 2008)
The major aim of this study is to determine and compare the distribution of bacteria and actinobacteria in Marion Island terrestrial habitats.
An assessment of the dietary intake of pregnant women in the West Coast / Winelands region, Western Cape Province: relation to low birth weight
(University of the Western Cape, 2008)
This secondary analysis aimed to develop dietary scores to assess the dietary intake of pregnant women in the West Coast/ Winelands region and determine the association with LBW. Further to determine the association between ...
The structure, function and engineering of a thermostable nitrile hydratase
(University of the Western Cape, 2008)
Nitrile hydratases (NHases) are enzymes that catalyse the conversion of organocyanides to amides via a non-hydrolytic hydration reaction. They are industrially relevant enzymes, currently used in the manufacture of ...
Genetic analysis of resistance to apple scab (Venturia inaequalis) in apple (Malus x domestica Borkh)
(University of the Western Cape, 2007)
Amongst the many problems facing the apple industry, apple scab is one of the most challenging experienced by producers. This disease is caused by Venturia inaequalis, which causes lesions to develop on both the fruit and ...