Browsing Magister Pharmaceuticae - MPharm by Title
Now showing items 47-66 of 140
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Efavirenz pre-formulation study : selection of a cyclodextrin inclusion complex or co-crystal complex for tabletting
(University of the Western Cape, 2015)Efavirenz is a non-nucleoside reverse transcriptase inhibitor used as an anti-retroviral for the treatment of human immunodeficiency virus (HIV) type I. It is classified as a class IΙ drug under the Biopharmaceutical ... -
The effect of co-crystallization and polymorphism on the physicochemical properties of amoxicillin tri-hydrate
(University of the Western Cape, 2013)Many active pharmaceutical ingredients (APIs) have poor physicochemical properties such as solubility, dissolution and chemical stability. Several strategies are used to enhance and improve these properties of the API. ... -
Effect of inhaled cationic poly-peptides on respiratory mechanics in the isolated perfused rat lung
(University of the Western Cape, 1998)The inhalation route is increasingly being considered as a viable option to deliver protein drugs into the body, but there has been few studies dealing with the safety of this strategy. The results of in vitro studies have ... -
The effectiveness of using pictograms and text on medication labels at primary healthcare facilities in Cape Town
(University of the Western Cape, 2020)Medication labels are often the only information available to patients after obtaining medication 3 from the pharmacy or other healthcare practitioners. Inappropriately designed medicine labelling 4 contributes to poor ... -
Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic ... -
Effects of the alkaloid present in the ethyl acetate: hexane (1 :4) fraction of Crinum macowanii on the isolated perfused rat heart
(University of the Western Cape, 2004)Crinum macowanii (CM) is used in traditional medicine in the treatment of various diseases including ischemic heart disease, rheumatic fever, cancer and skin diseases. The aqueous extract of CM bulbs was found have a ... -
Electronic nicotine delivery systems : approach to regulation in South Africa
(University of the Western Cape, 2015)Background: The explosion in the popularity and use of e- cigarettes over the last decade has raised concerns and incited intense discussions over their safety, efficacy and potential public health impact. Globally there ... -
Employee Perceptions of Corporate Social Responsibility within the Pharmaceutical Industry
(UWC, 2020)The role corporate social responsibility (CSR) plays amongst employees is underrated within the pharmaceutical industry, which focuses predominantly on external stakeholders and financial gain. The impact of CSR on these ... -
Ethionamide pharmacokinetics in multidrugresistant tuberculosis patients with and without HIVinfection
(University of the Western Cape, 2017)Many studies have investigated the pharmacokinetics (PK) of anti-tuberculosis drugs in tuberculosis patients. However, currently in South Africa, no studies have been done on ethionamide (ETH) PK in adult MDR-TB patients ... -
Evaluation of antihistamines for in vitro antimalarial activity against Plasmodium falciparum
(2010)The declining efficacy of antimalarial drugs against resistant Plasmodium falciparum strains in several endemic regions has amplified the world’s burden of neglected diseases. This has highlighted the need for alternate ... -
Evaluation of guidelines for clinical trials of traditional plant medicines
(University of the Western Cape, 2005)The World Health Organization estimates that 4 billion people use herbal medicine for some aspect of primary health care. These herbal products are however mostly used without the necessary clinical trial done to prove ... -
The evaluation of markers for quality control studies of flavonoid-containing medicinal preparations
(University of the Western Cape, 2004)Medicinal plant products in various forms have been available for the treatment of disease in both developing and developed countries for many years (Chan, 2003). Indigenous knowledge on the use of two plants, Artemisia ... -
The evaluation of microwave drying on the polymorphic characteristics of carbamazepine granules prepared by the wet granulation process.
(Univeraity of the Western Cape, 2006)The drying conditions of granules for tabletting prepared by the wet granulation process traditionally involve conduction, convection and radiation heat transfer. Despite various technological advances utilizing combinations ... -
Evaluation of rational use of medicines in public healthcare facilities
(University of the Western Cape, 2020)Access to quality healthcare in South Africa is known to be unequal, with those who can afford it, receiving the best quality healthcare services in the private sector, and those who cannot afford it, having to receive ... -
Evaluation of satherlandia frutescens for anti.cancer activity
(University of the Western Cape, 2002)The claim for anti-cancer activity of the plant Sutherlandiafrutescens was investigated against some cancer cell lines in-vitro and against a dichlorvos induced chemical carcinogenesis in-vivo. A preliminary phytochemical ... -
Evaluation of the anticonvulsant activity of Elytropappus rhinocerotis (L.f) Less
(University of the Western Cape, 2016)M.Pharm thesis, Discipline of Pharmacology, School of Pharmacy, University of the Western Cape. Epilepsy is a worldwide neurological disorder which is also prevalent in South Africa. Herbal medicines, besides orthodox ... -
Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta Graveolens L. in mice and rats
(University of the Western Cape, 2012)Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta graveolens L. in mice and rats FIRDOWS LOONAT M. Pharm. Pharmaceutical Sciences thesis: School of Pharmacy, University of the Western ... -
An Evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, Traditional Medicinal Plants used in the Western Cape
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifolia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
An evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifulia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
Evaluation of the pulmonary effects of the traditionally prepared Artemisia afra steam inhalation and nebulized aqueous extract and the possible involvement of flavonoid luteolin
(University of the Western Cape, 2006)Artemisia afra is a popular medicinal plant traditionally used to treat respiratory conditions such as asthma, bronchitis etc., most frequently as a steam inhalation. The effectiveness of this steam inhalation, its active ...
