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Novel aminoquinoline-polycyclic hybrid molecules as potential antimalarial agents
(University of the Western Cape, 2014)
Plasmodium falciparum malaria continues to be a worldwide health problem, especially in developing countries in Africa and is responsible for over a million fatalities per annum. Chloroquine (CQ) is low-cost, safe and was ...
An investigation into combined amorphous form of sufadoxine, pyrimethamine and azithromycin
(University of Western Cape, 2021)
Malaria remains one of the top mortality causes in the sub-Saharan African region, especially
among pregnant women and infants. Despite several measures being implemented within the
affected areas such as the use of ...
Structure-Based Virtual Screening of Selected Malaria Box Compounds Against a Multi-Staged Protein (Falstatin) in Plasmodium falciparum
(University of the Western Cape, 2021)
Malaria disease poses substantial health risks to many nations, especially in Africa, where it primarily affects pregnant women, children, and immunocompromised patients. However, current antimalarial drugs have limitations ...