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Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease that, despite all efforts devoted towards its
eradication, remains a threat to many countries including South Africa. Current diagnostic
assays do offer better performance than ...
The development of graphene oxide sheet- and polyanilino-immunosensor systems for lipoarabinomannan (LAM) tuberculosis biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease with adverse effect on a global scale. The disease is one of the major causes of death in sub-Saharan Africa. Nearly 70% of TB-infected persons are co-infected by the human ...
Investigating the functional interaction of transcription regulator CarD of Mycobacterium tuberculosis with Ribonucleic Acid Polymerase
(University of the Western Cape, 2014)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ...
Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
(2013)
Tuberculosis still remains one of the world’s killer diseases. Pyrazinamide (PZA) is one of
the most commonly prescribed anti-tuberculosis (anti-TB) drugs due to its ability to
significantly shorten the TB treatment ...
Mathematical modeling of the population dynamics of tuberculosis
(University of the Western Cape, 2016)
Tuberculosis (TB) is currently one of the major public health challenges in South Africa, and in many countries. Mycobacterium tuberculosis is among the leading causes of morbidity and mortality. It is known that tuberculosis ...
An assessment of current practice patterns of TB/HIV at primary healthcare clinics in the Western Cape and a needs assessment for clinic-based training among final year Pharmacy students
(University of the Western Cape, 2010)
Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in deaths of approximately 2 million people a year. South Africa (SA) has one of the highest annual TB incidences with an ...
Investigating the functional interaction of transcription regulator card of mycobacterium tuberculosis with ribonucleic acid polymerase
(2013)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ...
The use of dioxy MP 14 (stabilized aqueous chlorine dioxide) to control environmental airborne microorganisms
(2009)
Dioxy MP 14 is a locally developed form of stabilized chlorine dioxide in an aqueous medium. It has all the sanitizing properties of chlorine dioxide gas, a neutral compound of chlorine in the +IV oxidation state, which ...
Effects of nucleotide variation on the structure and function of human arylamine n-acetyltransferase 1
(2012)
The human arylamine N-acetyltransferase 1 (NAT1) is critical in determining the duration of action and pharmacokinetics of amine-containing drugs such as para-aminosalicylic acid and para-aminobenzoyl glutamate used in ...
Nanoparticulate of silver-modified poly (8-anilino-1-naphthalene sulphonic acid) nanobiosensor systems for the determination of Tuberculosis treatment drugs
(University of the Western Cape, 2011)
This study firstly reports the development and characterization of PVP-AgNPs, PANSA and PVPAgNPs/ PANSA nanocomposite on gold. AFM and TEM analyses revealed highly electroactive nanocomposites whose morphogy and properties ...