Browsing by Author "Meyer, Mervin"
Now showing items 21-28 of 28
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Investigating novel cis-acting regulatory elements involved in the regulation of heat shock response in cardiomyocytes
Fortuin, Ira (2013)Ischemic heart disease is a disease which is characterized by the reduced blood supply to the heart. According to WHO 2013, ischemic heart disease is one of the major causes of death globally. For this reason, it is ... -
Liposomal drug delivery to brain cancer cells
Boltman, Taahirah (University of the Western Cape, 2015)Neuroblastomas (NBs) are the most common solid extra-cranial tumours diagnosed in childhood and characterized by a high risk of tumour relapse. Like in other tumour types, there are major concerns about the specificity and ... -
Peptide functionalised gold nanorods for the selective eradication of target cells using photothermal therapy
Meyer, Miché Desline (University of the Western Cape, 2019)Cancer is one of the leading causes of death, worldwide. Mortality tolls are estimated to reach approximately 13.1 million in 2030. These statistics suggest that current therapeutic strategies are not effective. This is ... -
Proteome signature of breast cancer cells treated with fucoidan
Janodien, Fatima (University of the Western Cape, 2016)Breast cancer is responsible for a large portion of cancer-related deaths. Worldwide, incidence is increasing. Routinely-used treatments for breast cancer are invasive and are associated with a range of side-effects which ... -
Screening of plant-mediated nanoparticles for antifungal activity
de Beer, Irving (University of the Western Cape, 2020)Nanotechnology is spreading rapidly across the world as an extremely powerful technology. Nanoscience and nanotechnology are innovative scientific advancements that have been introduced only in this century. Nanotechnology ... -
Synthesis of peptide-loaded chitosan nanoparticles for the treatment of sexually transmitted infections (STI’s)
Phathekile, Bonke (University of Western Cape, 2019)Peptides are among the main drugs which attract much attention because of their great potential in treating sexually transmitted diseases and other chronic diseases. There has been a major challenge of delivering these ... -
Targeted delivery of GFP loaded polymeric nanoparticles to CD4 expressing cells using a CD4 specific aptamer
Mirfin, Tayla Michele (University of the Western Cape, 2020)Human Immunodeficiency Virus (HIV), which is the cause of Acquired Immunodefiency Syndrome (AIDS) is a major global public health issue affecting over 37 million people worldwide and is responsible for claiming over 32 ... -
Tumour specific targeted in vitro theranostics application of fabricated nanostructures in a multi-drug resistant ovarian carcinoma cell line
Taute, C.J.F (University of the Western Cape, 2013)Ovarian cancer is called the “Silent Killer” as it is often diagnosed in advanced stages of the disease or misdiagnosed which ends with a poor prognostic outcome for the patient. A high rate of disease relapse, a high ...