Browsing by Title
Now showing items 4244-4263 of 8878
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Identification and characterisation of novel cellulolytic genes using metagenomics
(University of the Western Cape, 2010)Metagenomics has been successfully used to discover novel enzymes from uncultured microorganisms in the environment. In this study, metagenomic DNA from a Malawian hot spring soil sample was used to construct a fosmid ... -
Identification and characterisation of potential virulence genes of Salmonella from rooibos tea
(University of the Western Cape, 2015)The aim of this study was to investigate the presence of Salmonella in the tea processing environment, to identify and detect potential virulence genes isolated from Salmonella in the tea, and to determine the antibiotic ... -
Identification and characterisation of sorghum bicolor heme oxygenase-1 (sbho1) gene and its role in conferring biotic and abiotic stress tolerance to plants
(University of the Western Cape, 2019)Biotic and abiotic stresses such as herbivore attack, pathogen infection, salinity, drought, cold, heat and UV radiation, are unfavourable conditions that affect plant growth and productivity globally (Fedoroff et al., ... -
Identification and characterisation of the role of endozepine in apoptosis induced by ceramide
(University of the Western Cape, 2003)Apoptosis is a form of programmed cell death and is required for the normal development, tissue homeostasis and survival of organisms. The identification of mutations that can lead to alterations in cell death not only ... -
Identification and characterization of microorganisms associated with marine macroalgae Splachnidium rugosum
(University of the Western Cape, 2014)Marine macroalgae are known to carry diverse bacterial communities which interact with their hosts in both harmful and beneficial ways. Algae hosts provide the bacteria with a rich source of carbon in the form of carbohydrate ... -
Identification and characterization of microRNAs and their putative target genes in Anopheles funestus s.s
(2013)The discovery of microRNAs (miRNAs) is one of the most exciting scientific breakthroughs in the last decade. miRNAs are short RNA molecules that do not encode proteins but instead, regulate gene expression. Over the past ... -
Identification and estimation of ecologically relevant flow indices for non-perennial rivers, South Africa
(University of the Western Cape, 2019)The importance of environmental flows and establishing the balance between hydrological response and ecological functioning of rivers has been globally recognised. Methods for determining environmental flows range from ... -
Identification and Molecular validation of Biomarkers for the accurate and sensitive diagnosis of bacterial and viral Pneumonia
(University of Western Cape, 2019)Pneumonia remains the major cause of death in children and the elderly and several efforts have been intensified to reduce the rate of pneumonia infection. The major breakthrough has been the discovery of certain biomarkers ... -
Identification and partial characterisation of a putative novel plant stress response gene from Arabidopsis thaliana.
(University of the Western Cape, 2000)Exposure of plants to stress results in the expression of plant genes whose products play a role in defence responses against the stress. Stress stimuli to which plants may be exposed are wounding, drought, salinity, ... -
Identification and prioritization of areas for riparian buffer restoration in the Sout River catchment, Overberg District, Western Cape
(University of the Western Cape, 2023)River catchments in areas dominated by agricultural activities are prone to contamination by nutrient-rich sediments whereby phosphorus is most concern. Phosphorus binds to fine sediments and gets transported to the ... -
Identification and quantification of chemicals of emerging concern (persistent organic and inorganic pollutants) in some selected marine environments of cape town, South Africa
(University of the Western Cape, 2020)The increasing evidence of chemicals of emerging concern (CECs) in water bodies is causing major concern around the world because of their toxicological effects upon humans and aquatic organisms. The release of wastewater ... -
Identification and ranking of pervasive secondary structures in positive sense single-stranded ribonucleic acid viral genomes
(University of the Western Cape, 2018)The plasticity of single-stranded viral genomes permits the formation of secondary structures through complementary base-pairing of their component nucleotides. Such structures have been shown to regulate a number of ... -
Identification and validation of micrornas for diagnosing type 2 diabetes : an in silico and molecular approach
(University of the Western Cape, 2015)Type 2 diabetes mellitus (T2DM), a metabolic disease characterized by chronic hyperglycemia, is the most prevalent form of diabetes globally, affecting approximately 95 % of the total number of people with diabetes i.e. ... -
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS remains one of the major causes of death in the world and mostly in sub-Saharan Africa. To date, neither ... -
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS still remains one of the major causes of death in the world and mostly in Sub-Saharan Africa. To date, ... -
Identification of a transducin (beta)-like 3 protein as a potential biomarker of prediabetes from rat urine using proteomics
(University of the Western Cape, 2010)Obesity is a globally increasing disease particularly in developing countries and among children. It is mainly caused by intake of diets high in fat and the lack of physical activity. Obesity is a risk factor for diseases ... -
The identification of aptamers against serum biomarkers of human tuberculosis
(University of the Western Cape, 2018)Tuberculosis (TB) is a global health problem and rated as the second leading cause of death after HIV/AIDS. Transmission of TB from one person to the next is very rapid in crowded communities. Therefore, it is crucial to ... -
Identification of bacterial pathogenic gene classes subject to diversifying selection
(University of the Western Cape, 2009)Availability of genome sequences for numerous bacterial species comprising of different bacterial strains allows elucidation of species and strain specific adaptations that facilitate their survival in widely fluctuating ... -
The identification of batting trends through a comparative analysis in Twenty20 cricket between Varsity Cup winning teams and the University of the Western Cape Cricket Club from its origin in 2015 – 2017
(University of the Western Cape, 2020)Over the years cricket has developed from a traditional and conservative game into an extremely lucrative sport, which requires a great deal of professionalism in all surrounding areas. In recent years cricket has evolved ... -
The identification of biologically important secondary structures in disease-causing RNA viruses
(University of the Western Cape, 2012)Viral genomes consist of either deoxyribonucleic acid (DNA) or ribonucleic acid (RNA). The viral RNA molecules are responsible for two functions, firstly, their sequences contain the genetic code, which encodes the viral ...
