Browsing by Subject "Pyrazinamide"
Now showing items 1-5 of 5
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Determination of pyrazinamide plasma concentrations using lc-ms and pharmacokinetics of pyrazinamide in patients with multidrug-resistant tuberculosis and in patients co-infected with multidrug-resistant tuberculosis and HIV
(2013)Tuberculosis and HIV are arguably South Africa’s largest and most important health issues. With drug-resistant strains of tuberculosis on the increase and little research on new drugs, there is an urgent need for research ... -
Development of nanobiosensors for phenolic endocrine disrupting compounds and anti- tuberculosis drugs
(2013)Tuberculosis still remains one of the world’s killer diseases. Pyrazinamide (PZA) is one of the most commonly prescribed anti-tuberculosis (anti-TB) drugs due to its ability to significantly shorten the TB treatment ... -
Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs
(University of Western Cape, 2020)Tuberculosis (TB) remains a global epidemic despite the fact that treatment has been available since the 1950’s. This disease is highly contagious and spreads via transmission of the Mycobacterium Tuberculosis (MTB) tubercle ... -
Nanoparticulate of silver-modified poly (8-anilino-1-naphthalene sulphonic acid) nanobiosensor systems for the determination of Tuberculosis treatment drugs
(University of the Western Cape, 2011)This study firstly reports the development and characterization of PVP-AgNPs, PANSA and PVPAgNPs/ PANSA nanocomposite on gold. AFM and TEM analyses revealed highly electroactive nanocomposites whose morphogy and properties ... -
Spectroelectrochemical graphene-silver/zinc oxide nanoparticulate phenotype biosensors for ethambutol and pyrazinamide
(University of the Western Cape, 2019)Tuberculosis (TB), a deadly disease second to HIV/AIDS, is a global health problem. Diagnosis of active tuberculosis is tedious and requires expensive procedures since there is no recognizable method for sole detection ...