An electrophysiological exploration into the Sertoli cell, utilizing plant extracts with a view to contraception

Abstract

Certa in medicinal plant extracts have been shown to have a contraceptive effect on male rats (Rajasekaran et al. , 1988) and mice (Kong et al., 1986). A possible site for the mechanism of action has been identified as the testis. The Sertoli cell s within the seminiferous tubules of the teste s are of fundamental importance to the developing sperm. These cells create a unique environment, which, without, would lead to the cessation of spermatogenesis (Gow et al. , 199 9). Know ledge of the Sertoli cell is thus essential in understanding the control of developing germ cells within the seminiferous tubules of the testis.