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The effect of kinetin and salt stress on pnp-a expression in erucastrum strigosum and arabidopsis thaliana
(University of the Western Cape, 2002)
In agriculture crop productivity is greatly affected by stresses such as salinity, drought,
temperature and honnonal changes of crop plants and responses to these stresses. Studies
have shown that a natriuretic peptide ...
Metagenomic analysis and characterization of microbial diversity from hydrothermal samples of El Tatio geyser field, Chile
(University of the Western Cape, 2012)
The El Tatio geyser field (ETGF) is the largest known geothermal field in Chile, forming part of a wide spectrum of extremophilic habitats in the country. The ETGF is NaCl rich, with high concentrations of toxic elements ...
Design and synthesis of polycyclic amine derivatives for sigma receptor activity
(2013)
New therapeutic strategies are needed for a diverse array of poorly understood neurological impairments. These include neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease, and the psychiatric ...
Investigating novel cis-acting regulatory elements involved in the regulation of heat shock response in cardiomyocytes
(2013)
Ischemic heart disease is a disease which is characterized by the reduced blood
supply to the heart. According to WHO 2013, ischemic heart disease is one of the
major causes of death globally. For this reason, it is ...
An in vitro study on the immunotoxicity of sewage effluents discharged into the Eerste River-Kuils river water catchment system
(2008)
"The aim of the study was to use in vitro human whole blood cultures to screen the water samples collected from the Eerste/Plankenbrug river system for cytotoxicity and inflammatory activity and for the first time investigate ...
The development and application of informatics-based systems for the analysis of the human transcriptome
(University of the Western Cape, 2003)
Despite the fact that the sequence of the human genome is now complete it has become clear that the elucidation of the transcriptome is more complicated than previously expected. There is mounting evidence for unexpected ...
Seasonal dynamics of edaphic bacterial communities in the hyper-arid namib desert
(2012)
The Namib Desert is a hyper-arid, coastal desert with limited bioavailable water and
nutrients; characteristics which collectively impose constraints on edaphic microbial
communities. Several studies in the Namib Desert ...
Novel genomic approaches for the identification of virulence genes and drug targets in pathogenic bacteria
(University of the Western Cape, 2001)
While the many completely sequenced genomes of bacterial pathogens contain all the determinants of the host-pathogen interaction, and also every possible drug target and recombinant vaccine candidate, computational tools ...
Low detection of exon skipping in mouse genes orthologous to human genes on chromosome 22
(University of the Western Cape, 2002)
Alternative RNA splicing is one of the leading mechanisms contributing towards transcript and protein diversity. Several alternative splicing surveys have confirmed the frequent occurrence of exon skipping in human genes. ...
Investigation of the intra-cellular localisation of Retinoblastoma Binding Protein 6 using immunofluorescence microscopy
(University of the Western Cape, 2017)
Human Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa protein that has been
implicated in a number of crucial cellular processes. It forms part of the mRNA 3'-end
processing complex in both humans and yeast, and it ...