Browsing Department of Biotechnology by Title
Now showing items 136-155 of 360
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Functional analysis of miRNA regulated genes in prostate cancer as potential diagnostic molecules
(University of the Western Cape, 2016)Prostate Cancer is the leading cause of cancer-related death in males in the Western world. It is a common biological disease originating from the reproductive system of the male namely, the prostate gland, usually in older ... -
Functional characterisation of a novel ferulic acid esterase from malawian hot spring metagenome
(2011)There has been a decline in the global fossil fuel reserves, due to an increasing demand for petroleum. Biofuels can be used as an alternative source of energy whereby biomass is converted to liquid fuels such as bioethanol. ... -
Functional characterisation of a thermophilic cellulase from a Malawian metagenomic library
(2013)Biofuels are currently recognised as the most viable source of energy to replace depleting fossil fuel reserves, with bioethanol the most popular alternative alcohol fuel. Producing bioethanol from agricultural waste ... -
Functional genomic characterization of fruit quality traits in apple (Malus x domestica Borkh)
(University of the Western Cape, 2009)The domesticated apple (Malus x domestica Borkh), belonging to the Malusgenus of the Rosaceae family, is one of the edible pomaceous fruits. Since it is one of the important commercial fruit crops worldwide, the quality ... -
Gallic acid modulates salt stress tolerance in soybean plants by regulating antioxidant capacity
(University of the Western Cape, 2017)Soybean [Glycine max L (mer)] is one of the top commodity crops in the world including South Africa (de Beer and Prinsloo, 2013). These small yet important podded legumes are a great source of protein and are used in many forms. -
Gene Discovery in Antarctic Dry Valley Soils
(University of the Western Cape, 2008)The metagenomic approach to gene discovery circumvents conventional gene and gene product acquisition by exploiting the uncultured majority of microorganisms in the environment. It was demonstrated in this study that ... -
The genease activity of mung bean nuclease: fact or fiction?
(University of the Western Cape, 2004)The action of Mung Bean Nuclease (MBN) on DNA makes it possible to clone intact gene fragments from genes of the malaria parasite, Plasmodium. This “genease” activity has provided a foundation for further ... -
Genetic analysis of mitochondrial DNA within Southern African populations.
(UWC, 2020)As human beings we are curious about our origin and ancestry. A curiosity has led to an investigation of human evolution and expansion across the world by means of population genetics and phylo-genetics by evaluating a ... -
¹Genetic analysis of red pigmentation in ‘bon rouge’ pears (Pyrus communis L.)
(University of Western Cape, 2014)European pear (Pyrus communis L.) is the third most important fruit in South Africa after citrus and apple. The Agricultural Research Council (ARC) breeding programme seeks to obtain a fully red coloured pear. Sports ... -
Genetic analysis of resistance to apple scab (Venturia inaequalis) in apple (Malus x domestica Borkh)
(University of the Western Cape, 2007)Amongst the many problems facing the apple industry, apple scab is one of the most challenging experienced by producers. This disease is caused by Venturia inaequalis, which causes lesions to develop on both the fruit and ... -
Genetic diversity of the Organic Cation Transporter 1 gene within the Cape Coloured Population
(University of the Western Cape, 2012)The aim of this study was to investigate the genetic diversity of the SLC22A1 gene and to deduce its possible pharmacogenetic implications within the Cape Coloured population of South Africa; a uniquely admixed population ... -
Genetic mapping of fruit quality traits in apple (malus x domestica borkh.)
(University of the Western Cape, 2011)Apple fruit quality is of utmost importance to apple farmers and breeders in the selection and commercialization of new cultivars. Fruit size, colour, texture, firmness and taste are all traits that affect the quality of ... -
Genome assembly of next-generation sequencing data for the Oryx bacillus : species of the Mycobacterium tuberculosis complex
(University of the Western Cape, 2011)Next generation sequencing (NGS) technology platforms have accelerated ability to produce completed genome assemblies. Recently, collaborators at Tygerberg Medical School outsourced the sequencing of Oryx bacillus, a ... -
Genome-wide identification and comprehensive analysis of transcriptionsl desert regions
(University of the Western Cape, 2009)The initiation of transcription in mammalian genomes predominatly occurs at 5' promoter regions, however increasingly initiation events have been observed within introns, coding exons and 3' UTRs. Nevertheless there ... -
Genomic and proteomic analysis of drought tolerance in Sorghum (Sorghum bicolor (L.) Moench)
(University of the Western Cape, 2014)Drought is the most complex phenomenon that remained to be a potential and historic challenge to human welfare. It affects plant productivity by eliciting perturbations related to a pathway that controls a normal, ... -
Genomic diversity and functional analysis of the solute carrier genes within indigenous African and Cape Admixed populations
(University of the Western Cape, 2016)Solute carrier transporters belonging to the major facilitator family of membrane transporter are increasingly being recognized as a possible mechanism to explain inter-individual variation in drug efficacy and response. ... -
The geographical analysis of the mitochondrial DNA control region found in southern African population's by using a bioinformatics approach
(University of the Western Cape, 2020)South Africa’s demographic complexity has been historically shaped by interethnic admixture between the native KhoiSan inhabitants and the Bantu expansion that started 3000 - 5000 YBP and reached South Africa about 1000 ... -
Green synthesis and characterization of gold nanoparticles from South African plants and their biological evaluations
(University of the Western Cape, 2019)The field of nanotechnology continues to offer solutions for biotechnologists whose target is to improve the quality of life by finding new therapies to combat diseases. Gold nanoparticles (AuNPs) have been showing great ... -
Green Synthesis and characterization of gold Nanoparticles using Green Alga Ulva Lactuca and evaluation of their Catalytric Role
(University of the Western Cape, 2016)Nanoparticles synthesized using typical chemical procedures have associated environmental risks because of the use of hazardous chemicals. With the ever-increasing potential application for nanomaterials, there is a growing ... -
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects
(University of the Western Cape, 2020)Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ...