Browsing Department of Biotechnology by Title
Now showing items 205-224 of 362
-
Investigating the effect of particle size on the antibacterial activity of gold nanoparticles
(University of the Western Cape, 2017)The increase of antibiotic- and/or multidrug-resistant bacteria has become a major global challenge. Killing of antibiotic-resistant bacteria requires a high dose of multiple, expensive drugs, which possess unfavourable ... -
Investigating the effect of particle size on the antibacterial activity of gold nanoparticles
(University of the Western Cape, 2017)The increase of antibiotic- and/or multidrug-resistant bacteria has become a major global challenge. Killing of antibiotic-resistant bacteria requires a high dose of multiple, expensive drugs, which possess unfavourable ... -
Investigating the functional interaction of transcription regulator CarD of Mycobacterium tuberculosis with Ribonucleic Acid Polymerase
(University of the Western Cape, 2014)Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ... -
Investigating the functional interaction of transcription regulator card of mycobacterium tuberculosis with ribonucleic acid polymerase
(2013)Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ... -
An investigation into the antimicrobial and immune modulatory effects of Sutherlandia frutescens and Salvia africana-lutea extracts and their respective biogenic nanoparticles
(University of the Western Cape, 2020)The prevalence of cancer and antibiotic-resistant microbes has led to the necessity of affordable, efficacious, non-toxic and easily accessible therapeutic approaches. There is numerous anecdotal evidence that African ... -
Investigation into the role of DWNN in cell death
(University of the Western Cape, 2004)Many genes are activated to influence the self-destruction programme of the cell. This programme entails synchronised instigation and implementation of numerous subprograms. The arrival of gene targeting aided in the ... -
Investigation of Guayule's Agronomic Performance and Agro-processing in South Africa
(University of the Western Cape, 2017)Guayule (Parthenium argentatum) is grown for its high quality hypoallergenic natural rubber latex production. The plant is native to the Chihuahua desert of North America and successful trials have been done in Europe, the ... -
Investigation of protein-metal ion and protein-protein interactions using mass spectrometry and nuclear magnetic spectroscopy
(University of Western Cape, 2014)Protein-protein interaction networks provide a global picture of cellular function and biological processes. Some proteins act as hub proteins, highly connected to others, whereas some others have few interactions. The ... -
Investigation of protein-protein interactions involving retinoblastoma binding protein 6 using immunoprecipitation and nuclear magnetic resonance spectroscopy
(University of Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with tumour suppressor proteins such as ... -
Investigation of protein-protein interactions involving Retinoblastoma Binding Protein 6 using immunoprecipitation and Nuclear Magnetic Resonance Spectroscopy
(University of the Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with tumour suppressor proteins such as ... -
Investigation of South African estuarine microbial species and genome diversity
(University of the Western Cape, 2006)A study of the microbial diversity in sediments of the Great Berg River estuary is carried out using modern molecular phylogenetic methods. The aim of this study was to determine the effect of (pollution by) the effluents ... -
Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
(University of the Western Cape, 2023)The incidence and prevalence of obesity and its related diseases has nearly tripled and is increasing at an alarming rate worldwide. Several modern methods for the management and treatment of obesity are available, with ... -
Investigation of the auto-ubiquitination and ubiquitination potentials of Retinoblastoma binding protein 6 and its binding to p53
(University of Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa human protein known to play an essential role in mRNA 3’-end processing, as well as functioning as an E3 ligase to catalyze ubiquitination and suppression of p53 and ... -
Investigation of the interaction of ceramide and acyl-coenzyme A with the mitochondrial associated protein, endozepine, using heteronuclear NMR
(University of the Western Cape, 2005)Endozepine is an alternative name for the testis-specific isoform of the acyl-CoA binding protein (t-ACBP). Acyl-CoA binding proteins form a highly conserved family of proteins, which bind long chain fatty acid esters with ... -
Investigation of the interactions of retinoblastoma binding protein-6 with transcription factors p53 and Y-Box Binding Protein-1
(2011)Retinoblastoma Binding Protein 6 (RBBP6) is a 250 kDa multi-domain protein that has been implicated in diverse cellular processes including apoptosis, mRNA processing and cell cycle regulation. Many of these functions are ... -
Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
(University of the Western Cape, 2017)Glycine max (soybean) is an important crop species globally as it is used as a protein-rich food and feed crop and as a source of oils used in the food and biofuel industry. However, the growth and yield of soybean is ... -
Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
(University of the Western Cape, 2017)Glycine max (soybean) is an important crop species globally as it is used as a protein-rich food and feed crop and as a source of oils used in the food and biofuel industry. However, the growth and yield of soybean is ... -
An investigation of the plants used medicinally In self-care in the Bredasdorp / Elim region
(University of the Western Cape, 2004)Much of the traditional medicinal plant knowledge is to a large extent known by the older generations. This knowledge is at risk of disappearing due to not being passed down to younger members of the respective families ... -
Investigation of the role of AtNOGC1, a guanylyl cyclase protein in response to abiotic and biotic stress
(University of the Western Cape, 2018)Agricultural production is one of the most important sectors which provide food for the growing world population which is estimated to reach 9.7 billion by 2050, thus there is a need to produce more food. Climate change, ... -
Investigation of the role of the ubiquitin-like DWNN domain in targeting Retinoblastoma Binding Protein 6 to nuclear speckles
(University of the Western Cape, 2018)Magister Scientiae - MSc (Biotechnology)