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Marine bacteria as a potential source for novel antimicrobial compounds
(University of the Western Cape, 2020)
The high rate of rediscovery of known compounds has led to a decline in the discovery of novel natural products. The high biodiversity of organisms growing in extreme conditions such as oceans has led to the increased ...
An investigation into the antimicrobial and immune modulatory effects of Sutherlandia frutescens and Salvia africana-lutea extracts and their respective biogenic nanoparticles
(University of the Western Cape, 2020)
The prevalence of cancer and antibiotic-resistant microbes has led to the necessity of affordable, efficacious, non-toxic and easily accessible therapeutic approaches. There is numerous anecdotal evidence that African ...
The geographical analysis of the mitochondrial DNA control region found in southern African population's by using a bioinformatics approach
(University of the Western Cape, 2020)
South Africa’s demographic complexity has been historically shaped by interethnic admixture between the native KhoiSan inhabitants and the Bantu expansion that started 3000 - 5000 YBP and reached South Africa about 1000 ...
De novo assembly of the rooibos genome
(University of Western Cape, 2020)
Rooibos (Aspalathus linearis) is endemic to the Cederberg region of South Africa, and one of
the few indigenous medicinal plants commercially cultivated in the country. International
interest in rooibos is growing, and ...
In vitro evaluation of Leonotis leonurus to validate its potential as an alternative anti-diabetic drug
(University of the Western Cape, 2022)
Africa is a rich source of medicinal plants with South Africa being known as a country with a
strong history of traditional healing, which masses a variety of approximately 30 000 flowering
plants and accounting for ...
Inter-individual genetic variation and the development of hypertension in a Xhosa African population of Eastern Cape, South Africa
(University of the Western Cape, 2022)
Cardiovascular diseases (CVD) are the leading cause of death globally, accounting for 18.6 million deaths. Hypertension (HTN) drives the global burden of CVD and is a leading cause of cardiovascular-related mortality with ...
Prevalence of uncontrolled hypertension and the pharmacogenomics of enalapril-induced adverse effects among patients in the Vhembe district
(University of the Western Cape, 2022)
Controlling blood pressure (BP) among individuals with hypertension is important in the
prevention of cardiovascular diseases (CVDs). However, maintaining optimal BP levels in
individuals who are prone to drug-induced ...