Department of Biotechnology: Recent submissions
Now showing items 61-80 of 362
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The effects of gallic acid on the membrane proteome and antioxidant system of wheat plants under salt stress
(University of Western Cape, 2020)Salt stress is a major abiotic stress that accounts for huge agricultural losses worldwide, which in turn threaten food security and sustainable agriculture. Salt triggers the excessive production of reactive oxygen species ... -
The C-economy, nutritional benefits and symbiotic performance of dual inoculated Phaseolus vulgaris (L.) plants, under variable nutrient conditions
(University of the Western Cape, 2010)The tripartite symbiosis between Phaseolus vulgaris, arbuscular-mycorrhiza and the nodule bacteria, Rhizobia have been the focus of many studies ranging over a number of decades, however these studies have failed to answer ... -
Targeted delivery of GFP loaded polymeric nanoparticles to CD4 expressing cells using a CD4 specific aptamer
(University of the Western Cape, 2020)Human Immunodeficiency Virus (HIV), which is the cause of Acquired Immunodefiency Syndrome (AIDS) is a major global public health issue affecting over 37 million people worldwide and is responsible for claiming over 32 ... -
Isolation and characterisation of leaf endophytic bacteria from weed plants for enhancing salinity stress tolerance in Brassica napus
(University of the Western Cape, 2020)In an ever changing environment, plants are constantly challenged by various abiotic stresses such as salinity, which limits global crop production. This directly affects food availability for the global population, which ... -
Isolation and characterization of bacterial endophytes for growth promotion of Phaseolus vulgaris under salinity stress
(University of the Western Cape, 2020)As the global human population grows, so does the demand for faster food production rates. Owing to this, agricultural practices have had to expand and move into semi-arid and arid regions, too, where frequent irrigation ... -
Biochemical characterization of β-xylosidase and β-glucosidase isolated from a thermophilic horse manure metagenomic library
(University of the Western Cape, 2020)The complete degradation of recalcitrant lignocellulose biomass into value-added products requires the efficient and synergistic action of lignocellulose degrading enzymes. This has resulted in a need for the discovery of ... -
Investigating the antimicrobial potential of Thalassomonas actiniarum
(University of the Western Cape, 2020)bioassay guided isolation approach was then used to isolate the high molecular weight antibacterial compound (50kDa-100kDa) from T. actiniarum fermentations. With common protein isolation, purification and detection methods ... -
Investigating the antimicrobial potential of Thalassomonas actiniarum
(University of Western Cape, 2020)The World Health Organisation predicts that by the year 2050, 10 million people could die annually as a result of infections caused by multidrug resistant bacteria. Individuals with compromised immune systems, caused by ... -
Biological approach to improving the evaporation rates of mine wastewater desalination brine treated in evaporation ponds
(University of the Western Cape, 2021)The disposal of brine effluent from inland wastewater desalination plants is a growing global problem with adverse economic and environmental implications because of the substantial cost associated with its disposal and ... -
Screening of plant-mediated nanoparticles for antifungal activity
(University of the Western Cape, 2020)Nanotechnology is spreading rapidly across the world as an extremely powerful technology. Nanoscience and nanotechnology are innovative scientific advancements that have been introduced only in this century. Nanotechnology ... -
The role of p-coumaric acid on physiological and biochemical response of chia seedling under salt stress
(University of the Western Cape, 2020)The role of phenolic acids in mitigating salt stress tolerance have been well documented. However, there are contradicting reports on the effect of exogenously applied phenolic acids on the growth and development of various ... -
Development of a COMT PCR multiplex to investigate resilience, anxiety and childhood trauma in a South African population
(University of the Western Cape, 2020)Anxiety, resilience and childhood trauma can be categorized as functional behavioural categories, with a wealth of research behind each. The research approach adopted for each, in most cases, is either from a genetic or ... -
Investigation of protein-protein interactions involving retinoblastoma binding protein 6 using immunoprecipitation and nuclear magnetic resonance spectroscopy
(University of Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with tumour suppressor proteins such as ... -
Investigation of the auto-ubiquitination and ubiquitination potentials of Retinoblastoma binding protein 6 and its binding to p53
(University of Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa human protein known to play an essential role in mRNA 3’-end processing, as well as functioning as an E3 ligase to catalyze ubiquitination and suppression of p53 and ... -
Investigation of protein-protein interactions involving Retinoblastoma Binding Protein 6 using immunoprecipitation and Nuclear Magnetic Resonance Spectroscopy
(University of the Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with tumour suppressor proteins such as ... -
Isolation and characterization of plant growth promoting endophytic bacteria from Medicago lupulina for enhanced drought tolerance in Maize
(University of the Western Cape, 2019)Maize is one of the major staple foods in many African nations however, this crop is sensitive to environmental stressors. Drought is a major environmental stressor affecting maize production. Due to global warming, drought ... -
Marine bacteria as a potential source for novel antimicrobial compounds
(University of the Western Cape, 2020)The high rate of rediscovery of known compounds has led to a decline in the discovery of novel natural products. The high biodiversity of organisms growing in extreme conditions such as oceans has led to the increased ... -
Antimicrobial, anticancer and catalytic activities of green synthesized Avocado seed extract-gold nanoparticles
(University of the Western Cape, 2019)Nature through billions of years of trial and error has produced an immeasurable amount of natural systems like plants, birds and animals. The intelligence of nature is hidden in these natural systems and researchers are ... -
De novo assembly of the rooibos genome
(University of Western Cape, 2020)Rooibos (Aspalathus linearis) is endemic to the Cederberg region of South Africa, and one of the few indigenous medicinal plants commercially cultivated in the country. International interest in rooibos is growing, and ... -
Nanoformulation of Artemisia afra and its potential biomedical applications in type 2 diabetes
(University of Western Cape, 2019)Current research classifies Type 2 diabetes as most prevalent non-communicable diseases in South Africa. Approximately 285 million people are affected globally with an expected increase to 595 million by the year 2035. ...