Browsing Philosophiae Doctor - PhD (Biotechnology) by Author "Meyer, Mervin"
Now showing items 1-7 of 7
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Analysis, expression profiling and characterization of hsa-miR-5698 target genes as putative dynamic network biomarkers for prostate cancer: a combined in silico and molecular approach
Lombe, Chipampe Patricia (University of the Western Cape, 2019)2018, the International Agency for Research on Cancer (IARC) estimated that prostate cancer (PCa) was the second leading cause of death in males worldwide. The number of deaths are expected to raise by 50 % in the next ... -
Aptamer selection against GFRa1 for its application in the prognosis of breast cancer
Swartz, Lauren Taryn (University of the Western Cape, 2019)Breast cancer is the second most common cancer amongst South African women. Despite ongoing efforts to combat breast cancer, current prognostic and/or therapeutic monitoring methods are limited since very little improvement, ... -
Development of a receptor targeted nanotherapy using a proapoptotic peptide
Sibuyi, Nicole Remaliah Samantha (University of the Western Cape, 2015)The prevalence of obesity amongst South Africans is alarming, with more than 29% of men and 56% of women considered to be obese. Angiogenesis, a process for development of new blood vessels play a major role in growth and ... -
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
Drah, Mustafa (University of the Western Cape, 2015)Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ... -
Green synthesis and characterization of gold nanoparticles from South African plants and their biological evaluations
Elbagory, Abdulrahman Mohammed Mohammed Nagy (University of the Western Cape, 2019)The field of nanotechnology continues to offer solutions for biotechnologists whose target is to improve the quality of life by finding new therapies to combat diseases. Gold nanoparticles (AuNPs) have been showing great ... -
In silico and molecular validation of identified putative genes and functional analysis of a N K G2D ligand as a breast cancer biomarkers
Bankole, Habeeb Adebodun (University of the Western Cape, 2015)The current diagnostic, prognostic, predictive and therapeutic monitoring methods used for breast cancer are limited. Thus, research into more specific, sensitive and effective strategies is required. Breast cancer is ... -
Tumour specific targeted in vitro theranostics application of fabricated nanostructures in a multi-drug resistant ovarian carcinoma cell line
Taute, C.J.F (University of the Western Cape, 2013)Ovarian cancer is called the “Silent Killer” as it is often diagnosed in advanced stages of the disease or misdiagnosed which ends with a poor prognostic outcome for the patient. A high rate of disease relapse, a high ...