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Now showing items 31-40 of 98
The implementation of sub-typing techniques to determine the diversity of L. monocytogenes strains adapted to the food processing environment and their association with human listeriosis cases
(University of the Western Cape, 2011)
Listeria monocytogenes has been established as a food-borne pathogen since the early 1980s and has become a big concern for the food industry and Public Health authorities (Doyle 2001; Oliveira et al. 2003; Capita et al. ...
Modulation of soybean and maize antioxidant activities by caffeic acid and nitric oxide under salt stress
(University of Western Cape, 2012)
Molecular Characterisation of the Brassinosteroid, Phytosulfokine and cGMP-dependent Responses in Arabidopsis thaliana
(University of the Western Cape, 2010)
In this thesis, we have firstly cloned and expressed the domains that harbours the putative catalytic GC domain in these receptor molecules and demonstrate that these molecules can convert GTP to cGMP in vitro. Secondly, ...
Solution structure of the RING finger domain from the human splicing-associated protein RBBP6 using heteronuclear Nuclear Magnetic Resonance (NMR) spectroscopy
(2009)
Retinoblastoma-binding protein 6 (RBBP6) is a multi-domain human protein known to play a role in mRNA splicing, cell cycle control and apoptosis. The protein interacts with tumour suppressor proteins p53 and pRb and recent ...
A yeast 2-hybrid screen to identify and characterize interaction partners of the cancer associated protein retinoblastoma binding protein 6
(2009)
Retinoblastoma binding protein 6 (RBBP6) is a 250 kDa protein that is
implicated in mRNA processing and ubiquitination functions and has been
shown to be highly up-regulated in a number of cancers. In humans and mice,RBBP6 ...
Identification of ruantitative trait loci controlling the requirement for chilling in vegetative budbreak in apple (Malus x domestica Borkh.)
(2008)
The domesticated apple (Malus x domestica Borkh.) has been distributed into diverse climatic conditions worldwide for commercial production of fruit. Apple trees need exposure to cold temperatures, referred to as chill ...
Structural characterisation of the interaction between RBBP6 and the multifunctional protein YB-1
(University of the Western Cape, 2010)
As a means of further localising the interaction, truncated fragments derived from the C-terminal region of YB-1, were tested for their interaction with the RING finger domain of RBBP6 using three different assays: a ...
Molecular detection and characterisation of RNA viruses of honeybees
(University of the Western Cape, 2009)
Propagation methods for honeybee viruses have not changed since these viruses were discovered. There are no suitable cell lines or cell culture techniques available for honeybee viruses. Honeybee viruses have to be manually ...
Studies on the population genetics of Euphausiids: a comparison of patterns in plagic taxa displaying different distributions and life-histories
(University of the Western Cape, 2006)
The systematic and population genetic relationships were characterised for three ecologically related euphausiid species: Euphausia lucens, E. recurva and E. vallentini. These species have different geographical distributions ...
Transcription regulation and candidate diagnostic markers of esophageal cancer
(University of the Western Cape, 2009)
Esophageal cancer (EC) ranks among the ten most frequent cancers worldwide. Mortality rates associated with EC are very similar to the incidence rates due to the relatively late stage of diagnosis and the poor efficacy of ...