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Development and characterization of pro-apoptotic drug candidates for anticancer drug discovery
(2013)
Cancer is one of the leading causes of death worldwide. According to the WHO, cancer accounted for 7.4 million deaths world wide in 2004. The metallo-compound cisplatin has been used for years as an effective antitumor ...
Identification and characterisation of the role of endozepine in apoptosis induced by ceramide
(University of the Western Cape, 2003)
Apoptosis is a form of programmed cell death and is required for the normal development, tissue homeostasis and survival of organisms. The identification of mutations that can lead to alterations in cell death not only ...