Browsing Magister Pharmaceuticae - MPharm by Author "School of Pharmacy"
Now showing items 1-14 of 14
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Acute and chronic toxicity of the flavonoid-containing plant, Artemisia afra in rodents
Mukinda, James Tshikosa (University of the Western Cape, 2005)The aim of this study was to investigate the possible toxicity of the flavonoid-containing plant, Artemisia afra and especially establish the safety of the aqueous extract of this plant after acute and chronic administration ... -
An assessment of current practice patterns of TB/HIV at primary healthcare clinics in the Western Cape and a needs assessment for clinic-based training among final year Pharmacy students
Tokosi, Oluwatoyin Iyabode Abiola (University of the Western Cape, 2010)Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in deaths of approximately 2 million people a year. South Africa (SA) has one of the highest annual TB incidences with an ... -
Cardiovascular effects of Leonotis leonurus extracts in normotensive rats and in isolated perfused rat heart
Obikeze, Kenechukwu (University of the Western Cape, 2004)This thesis discussed the cardiovascular effects of the aqueous leaf extract and a fraction of the methanol extract of Leonotis leonurus, a plant commonly used in traditional medicine in South Africa for the treatment of ... -
Comparison of the sutherlandioside B levels in two commercially available Sutherlandia frutescence preparations and the effect of elevated temperature and humidity on these levels
Joseph, Ashton Edward (University of the Western Cape, 2009)Sutherlandia frutescens (tribe Galegeae, Fabaceae), is a popular medicinal plant traditionally used in South Africa. In 2000, a company called Phyto Nova (Pty) Ltd. initiated large-scale cultivation and contract manufacturing ... -
The design, preparation and evaluation of Artemisia Afra and placebos in tea bag dosage form suitable for use in clinical trials
Dube, Admire (University of the Western Cape, 2006)Artemisia Afra, a popular South African traditional herbal medicine is commonly administered as a tea infusion of the leaves. However, clinical trials proving it safety and efficacy are lacking mainly due to the absence ... -
Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart
Khan, Fatima (University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic ... -
Evaluation of guidelines for clinical trials of traditional plant medicines
Van Wyk, Anthea (University of the Western Cape, 2005)The World Health Organization estimates that 4 billion people use herbal medicine for some aspect of primary health care. These herbal products are however mostly used without the necessary clinical trial done to prove ... -
The formulation and evaluation of rapid release tablets manufactured from Artemisia Afra plant material
Komperlla, Mahesh Kumar (University of the Western Cape, 2004)Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing ... -
The formulation, manufacture and evaluation of capsules containing freeze-dried aqueous extracts of Leonotis Leonorus or Mentha Longifolia
Ma, Haiqiu (University of the Western Cape, 2006)Leonotis leonorus and Mentha longifolia are two herbs commonly used in South Africa, mostly in oral liquid dosage forms. Several disadvantages are associated with these traditional dosage forms which can perhaps be remedied ... -
An investigation into the relationship between personality type, as measured by the Keirsey Bates Temperament Sorter, choice of practice setting and job satisfaction of pharmacists who graduated from the University of the Western Cape over the period 1990-2005
Le Roux, S.M. (University of the Western Cape, 2006)For the study the Keirsey Bates Temperament Sorter was completed by 602 pharmacy students during their study period at the University of the Western Cape. The results showed that the pharmacy students had a tendency towards ... -
Pharmaceutical evaluation of phela capsules Used as traditional medicine
Sehume, Brian J. (University of the Western Cape, 2010)In conclusion, the results obtained firstly indicated that the BP, EMEA and WHO were in fairly good agreement on the criteria and specifications that can be used to assesses the pharmaceutical quality of a traditional plant ... -
Pharmacological evaluation of antidiarrhoeal and antidiabetic activities of Syzygium Cordatum Hochst. ex C. Krauss
Deliwe, Mzonke (University of the Western Cape, 2011)Syzygium cordatum is a medicinal plant indigenous to South Africa and Mozambique, commonly used to treat stomach aches, diabetes, respiratory problems and tuberculosis. In spite of the folklore use, adequate scientific ... -
Pharmacological evaluation of some central nervous system effects of Cotyledon Orbiculata
Kabatende, Joseph (University of the Western Cape, 2005)The use of traditional medicine through the use of medicinal plants in Africa and especially in South Africa has long been considered an important characteristic of people's daily lives and socio-cultural heritage. Cotyledon ... -
Treatment outcomes in patients infected with multidrug resistant tuberculosis and in patients with multidrug resistant tuberculosis coinfected with human immunodeficiency virus at Brewelskloof Hospital
Adewumi, Olayinka Anthony (University of the Western Cape, 2012)Many studies have reported low cure rates for multidrug-resistant tuberculosis (MDRTB) patients and MDR-TB patients co-infected with human immunodeficiency virus (HIV). However, little is known about the effect of HIV ...