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Laccases from actinomycetes for lignocellulose degradation
(University of the Western Cape, 2012)
Lignocellulose has a complex structure composed mainly of lignin, hemicellulose and cellulose. Several enzymes are needed for the degradation of lignocellulose into simple sugars. Actinomycetes are known to produce laecases ...
The development of functionalized metallic nanoparticles for the treatment of brain cancer
(University of the Western Cape, 2019)
Cancers of the nervous system often result from abnormal and uncontrolled growth of cells in nervous tissue. Glioblastoma Multiforme (GBM) and neuroblastoma (NB) are among the most common nervous system-associated cancers ...
Novel gold nanoparticles of drought tolerance enabler GYY4137
(University of the Western Cape, 2019)
Different nanoparticles have the ability to improve plant tolerance to drought stress. In the study we report for the first time novel morpholin-4-ium 4-methoxyphenyl (morpholino) phosphinodithioate capped- gold nanoparticles ...
Comparative analysis of molecular and physiological responses of two canola genotypes to drought stress
(University of the Western Cape, 2016)
Food security has always been one of the priority concerns in Africa, and it is mostly
threatened by drought stress due to climate change. Drought-induced stress is one of the serious limiting factors of plant production, ...
Genome assembly of next-generation sequencing data for the Oryx bacillus : species of the Mycobacterium tuberculosis complex
(University of the Western Cape, 2011)
Next generation sequencing (NGS) technology platforms have accelerated ability to
produce completed genome assemblies. Recently, collaborators at Tygerberg Medical
School outsourced the sequencing of Oryx bacillus, a ...
Screening bacterial symbionts of marine invertebrates for ribosomally synthesized natural products
(University of the Western Cape, 2016)
Pharmaceutical research and development strategies rely on the constant discovery of novel natural products as potential drugs. Recent studies have shown that the
microorganisms associated with sponges are the true producers ...
Microbial diversity of the Namib Desert salt pans
(University of the Western Cape, 2015)
Salt pans are a characteristic feature of many dry deserts. The microbial communities inhabiting salt pans are thought to be particularly complex and are generally dominated by halophilic microorganisms. Although saline ...
Development of genotyping systems for pharmacogenomics profiling
(University of the Western Cape, 2016)
Genetic variability in genes encoding drug metabolizing enzymes, transporters and targets are known to be the main factors of inter-individual differences in therapeutic outcome. Genetic factors are estimated to be responsible ...
Proteomic and SNP analysis of the Cadherin 10 type-II (CDH10) gene, in the South African autistic population
(University of the Western Cape, 2013)
Autism or autism spectrum disorder (ASD) is a very diverse neurological disorder that manifests specifically in children and infants between the ages of two to three years of age. An individual suffering is deemed as ...
Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa
(University of the Western Cape, 2012)
Campylobacter species are the most common bacteria associated with acute diarrhoea and is responsible for 400 to 500 million reported cases globally. It is not uncommon for 35% to 85% of chicken flocks to be infected with ...