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Coding of tsetse repellents by olfactory sensory neurons: towards the improvement and the development of novel tsetse repellents
(University of the Western Cape, 2020)
Tsetse flies are the biological vectors of human and animal trypanosomiasis and hence representant medical and veterinary importance. The sense of smell plays a significant role in tsetse and its ecological interaction, ...
Coding of tsetse repellents by olfactory sensory neurons: towards the improvement and the development of novel
(University of the Western Cape, 2020)
Tsetse flies are the biological vectors of human and animal trypanosomiasis and hence representant medical and veterinary importance. The sense of smell plays a significant role in tsetse and its ecological interaction, ...
Computational analysis of multi-omic data for the elucidation of molecular mechanisms of neuroblastoma
(University of Western Cape, 2021)
Neuroblastoma is the most common extracranial solid tumor in childhood. The survival rates of patients with neuroblastoma, especially those in the high-risk category, are still low despite varied therapies. The detailed ...
Coding of tsetse repellents by olfactory sensory neurons: towards the improvement and the development of novel tsetse repellents
(University of Western Cape, 2021)
Tsetse flies are the biological vectors of human and animal trypanosomiasis and hence representant medical and veterinary importance. The sense of smell plays a significant role in tsetse and its ecological interaction, ...
Optimisation of proteomics techniques for archival tumour blocks of a South African cohort of colorectal cancer
(University of Western Cape, 2020)
Tumour-specific protein markers are usually present at elevated concentrations in patient biopsy tissue; therefore tumour tissue is an ideal biological material for studying cancer proteomics and biomarker discovery studies. ...
Next generation sequencing approaches for novel gene discovery in South African Parkinson’s disease families
(University of the Western Cape, 2022)
In the last decade, next-generation sequencing (NGS) approaches have revolutionised
the study of human genomics, particularly aiding the understanding of genetic diseases. Parkinson’s
disease (PD) is a complex neurodegenerative ...
Development of an operon detection algorithm to analyze gene regulation in drug resistant Mycobacterium tuberculosis
(University of the Western Cape, 2022)
In prokaryotes, operon structures often form to allow microorganisms to respond rapidly and efficiently to changing environmental conditions. Operons are sets of neighbouring genes which are co-regulated and co-transcribed. ...
Novel genomic biomarkers for pediatric and adult acute myeloid leukemia
(University of the Western Cape, 2023)
Acute myeloid leukemia (AML) is a heterogeneous type of blood cancer that affects individuals of all ages. AML patients are categorized into favorable, intermediate, and adverse risks based on patients' genomic features ...
Genomic epidemiology of Rift Valley fever in East Africa
(University of the Western Cape, 2023)
Rift Valley fever (RVF) is a climate-driven zoonotic disease of significant importance to public and livestock health given its epidemic potential. The disease was first identified in 1930 in the great rift valley region ...
Investigating genetic diversity and microRNA of Hermetia illucens (the black soldier fly) to breed for mass production of a novel sustainable protein
(University of the Western Cape, 2023)
Introduction: A new sustainable source of protein is needed to meet the demands of the growing global population. Insect meal is a suitable replacement, and the black soldier fly (BSF) is the most used insect in industrial ...