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    Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors 

    Adegoke, Yusuf Adeyemi (University of Western Cape, 2020)
    Natural products have been an important source of drugs and novel lead compounds in drug discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise to medicinally relevant agents. ...
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    Novel norbornane derivatives as potential neuroprotective agents 

    Egunlusi, Ayodeji Olatunde (University of Western Cape, 2020)
    Neurodegenerative disorders are characterised by progressive loss of the brain’s physiological functions as a result of gradual degeneration of neurons in the central nervous system. Even though they are classified as ...
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    Selected antiretroviral and anti-tuberculosis drug combinations by non-covalent bonding 

    Ngilirabanga, Jean Baptiste (University of Western Cape, 2021)
    Treatment of the human immunodeficiency virus (HIV) and tuberculosis (TB) infections have become very complicated due to the advent of drug resistance. Drug combinations offer an alternative approach to reducing the emergence ...
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    Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system 

    Ahmed, Rami M. Y. (University of the Western Cape, 2020)
    Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ...

    Discovery of antibacterial lead compounds from marine organisms 

    Afolayan, Omolola (University of the Western Cape, 2020)
    Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ...

    Pharmacological Characterization and Chemo-informatics analysis of Compounds from Leonotis leonurus. 

    Chioma O N, Oghenetega (2021)
    The central nervous system (CNS), consisting of the brain and the spinal cord, is responsible for integrating sensory information and influencing most bodily functions . The CNS is protected from toxic and pathogenic ...

    Pharmacological characterization and chemo-informatics analysis of compounds from leonotis leonurus 

    Oghenetega, Chioma O N (University of Western Cape, 2021)
    The central nervous system (CNS), consisting of the brain and the spinal cord, is responsible for integrating sensory information and influencing most bodily functions . The CNS is protected from toxic and pathogenic ...

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    AuthorAdegoke, Yusuf Adeyemi (1)Afolayan, Omolola (1)Ahmed, Rami M. Y. (1)Chioma O N, Oghenetega (1)Egunlusi, Ayodeji Olatunde (1)Ngilirabanga, Jean Baptiste (1)Oghenetega, Chioma O N (1)SubjectAlzheimer’s disease (2)Drug likeness (2)Leonotis leonurus (2)Tuberculosis (2)ADMET (1)Antibacterial (1)Antibiotics (1)Asparagine (1)Calcium influx (1)Central nervous system (1)... View MoreDate Issued2020 (4)2021 (3)Has File(s)true (7)

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