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Now showing items 11-20 of 30
Selected antiretroviral and anti-tuberculosis drug combinations by non-covalent bonding
(University of Western Cape, 2021)
Treatment of the human immunodeficiency virus (HIV) and tuberculosis (TB) infections have become very complicated due to the advent of drug resistance. Drug combinations offer an alternative approach to reducing the emergence ...
An investigation of the production of non-coated sustained release beads by extrusion and Spheronization
(University of the Western Cape, 1995)
The popularity and increasing complexity of sustained release dosage forms has resulted in increased costs to the patient. One approach to achieve cheaper, yet effective, sustained release medication is through the ...
The formulation and evaluation of indomethacin tablets
(University of the Western Cape, 1998)
The overall objective of this research is to attempt to produce, by direct compression,
indomethacin tablets which have good dissolution characteristics and an improved
bioavailability profile, when compared to the capsule ...
Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system
(University of the Western Cape, 2020)
Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ...
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)
Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ...
Pharmacological Characterization and Chemo-informatics analysis of Compounds from Leonotis leonurus.
(2021)
The central nervous system (CNS), consisting of the brain and the spinal cord, is responsible for
integrating sensory information and influencing most bodily functions . The CNS is protected from
toxic and pathogenic ...
Pharmacist educational outreach for improved primary care of asthma in children
(University of the Western Cape, 2001)
Underdiagnosis and undertreatment of asthma in children are barriers to optimal health care delivery and health, incurring substantial costs to both the families and health services. A tailored multifaceted educational ...
An investigation into the medicinal properties of Tulbaghia alliacea phytotherapy
(University of the Western Cape, 2009)
The reproductive health of individuals is severely compromised by HIV infection, with candidiasis being the most prevalent oral complication in patients. Although not usually associated with severe morbidity, oropharyngeal ...
Effects of Leonotis leonurus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)
An aqueous extract prepared from the leaves and smaller stems of Leonotis leonurus
was used to investigate the potential effects on certain cardiovascular parameters,
such as left ventricular systolic pressure, end-diastolic ...
A Reductionistic Epistemology utilizing Brain Laterality which Investigates Pharmacists' Ideal Interactive Environment
(University of the Western Cape, 2018)
The brain laterality of pharmacists may influence where the pharmacists are best suited to work. Brain laterality refers to the asymmetry of the hemispheres of the brain with regard to specific cognitive functions, such ...