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Now showing items 31-40 of 219
Quantum dots-amplified electrochemical cytochrome P450 phenotype sensor for tamoxifen, a breast cancer drug
(University of the Western Cape, 2017)
Breast cancer is regarded as the most common cancer in South Africa and its rate of
occurrence is increasing. About one in every 31 South African women are at the risk of
developing breast cancer and early diagnosis and ...
Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease that, despite all efforts devoted towards its
eradication, remains a threat to many countries including South Africa. Current diagnostic
assays do offer better performance than ...
Fabrication of type-I indium-based near-infrared emitting quantum dots for biological imaging applications
(University of the Western Cape, 2013)
Semiconductor nanocrystals or quantum dots (QDs) are fluorescent nanometer-sized particles
which have physical dimensions that are smaller than the excitonic Bohr radius, large surface
area-to-volume ratios, broad ...
Detection of selective tyrosinase inhibitors from some South African plant extracts of lamiaceae family
(University of the Western Cape, 2016)
Various dermatological disorders, such as formation of black pigmented patches on the surface of the skin arise from the over-activity of tyrosinase enzyme's degenerative action. This enzyme is further implicated in the ...
The preparation of an immunosensor for the detection of microcystins and nodularins by immobilisation of a labelled antibody onto a polymer modified electrode
(University of the Western Cape, 2011)
South African dams and reservoirs are increasingly showing the propensity to support sustained populations of Cyanobacteria (blue green algae). These photosynthetic bacteria occur throughout the world and can rapidly form ...
Quantum dot sensitized estrogen receptor alpha-recombinant protein electrochemical biosensor for 17-beta estradiol
(University of the Western Cape, 2016)
Estrogens play an extraordinary role in the endocrine system regulation through the stimulation and regulation of endocrine pathways. 17β-estradiol is one of the final metabolites in estrogen regulation by hydroxylase ...
The development of graphene oxide sheet- and polyanilino-immunosensor systems for lipoarabinomannan (LAM) tuberculosis biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease with adverse effect on a global scale. The disease is one of the major causes of death in sub-Saharan Africa. Nearly 70% of TB-infected persons are co-infected by the human ...
Development of Schiff base electrochemical sensors for the evaluation of polycyclic aromatic hydrocarbons in aqueous medium
(University of the Western Cape, 2017)
A novel monomer (N,N'-Bis-(1H-pyrrol-2-ylmethylene)-benzene-1,2-diamine-BPPD) was
derived from the condensation reaction between o-phenylenediamine and a pyrrole derivative. The
monomer was polymerized electrochemically ...
Electrochemical in-situ polymerization of graphene oxide/conducting star copolymer nanocomposite as supercapacitor electrode
(University of the Western Cape, 2017)
These days there are deep concerns over the environmental consequences of the rate of
consumption of energy from non-renewable sources because of the accelerated increase in greenhouse effect. There is, therefore, increasing ...
Overoxidized polypyrrole-osmium telluride quantum dots immunosensor for prostate specific antigen – A cancer biomarker.
(University of the Western Cape, 2014)
Prostate cancer is a deadly disease that occurs in the male’s prostate gland. A prostate gland is a walnut structure that forms part of the male’s reproductive system. Prostate cancer is caused by high level than normal ...