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Evaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening models

dc.contributor.advisorSyce, James A.
dc.contributor.advisorJoubert, E
dc.contributor.advisorMalherbe, C.J
dc.contributor.authorMatrose, Albertina Neliswa
dc.date.accessioned2015-06-03T14:57:20Z
dc.date.available2015-06-03T14:57:20Z
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/11394/4262
dc.descriptionMasters of Scienceen_US
dc.description.abstractThe aim of this study was therefore to evaluate the antioxidant and anti-diabesity potential of a hot water extract of C. maculata in non-cell based assays and correlate the activities with phenolic composition. Total antioxidant capacity (TAC) was assessed in terms of free radical scavenging and iron reducing ability. The DPPH, ABTS, ORAC and FRAP assays were employed. Anti-diabesity potential was assessed in terms of the inhibition of the digestive enzymes, α-glucosidase and pancreatic lipaseen_US
dc.language.isoenen_US
dc.publisherUniversity of the Western Capeen_US
dc.subjectObesityen_US
dc.subjectDiabetesen_US
dc.subjectOxidative stressen_US
dc.subjectCyclopia maculataen_US
dc.subjectAntioxidant capacityen_US
dc.subjectDPPH, ABTS, ORAC and FRAPen_US
dc.subjectTotal polyphenol contenten_US
dc.subjectLipase inhibitionen_US
dc.subjectα-Glucosidase inhibitionen_US
dc.subjectEffect of fermentationen_US
dc.subjectHPLC-DAD-BCDen_US
dc.titleEvaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening modelsen_US
dc.typeThesisen_US
dc.rights.holderUniversity of the Western Capeen_US


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