Browsing Faculty of Natural Science by Title
Now showing items 583-602 of 2560
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The development of a single nucleotide polymorphism database for forensic identification of specified physical traits
(University of the Western Cape, 2009)Many Single Nucleotide Polymorphisms (SNPs) found in coding or regulatory regions within the human genome lead to phenotypic differences that make prediction of physical appearance, based on genetic analysis, potentially ... -
Development of a small-scale electro-chlorination system for rural water supplies
(2010)To address the urgent need for safe potable water in South Africa’s rural areas, sustainable systems for water disinfection at the village-scale of operation are required.In this thesis, the development of a small-scale ... -
The development of a woman’s health handbook in the Western Cape
(2010)Background:The Project reported on in this thesis took place between 2003 and 2006 and focused on the problem of high rates of low birth weight in the West Coast /Winelands area of the Western Cape Province, South Africa. ... -
Development of amperometric biosensor with cyclopentadienylruthenium (II) thiolato schiff base self-assembled monolayer (SAM) on gold
(University of the Western Cape, 2007)A novel cyclopentadienylruthenium(II) thiolato Schiff base, [Ru(SC6H4NC(H)C6H4OCH2CH2SMe)(η5-C2H5]2 was synthesized and deposited as a selfassembled monolayer (SAM) on a gold electrode. Effective electronic communication ... -
Development of an actinobacteria based in vitro transcription and translation systems
(University of the Western Cape, 2015)Heterologous metagenomic screening strategies have relied largely on the construction of DNA libraries and screening in Escherichia coli to access novel enzymes. There is an increased demand for the identification of novel ... -
Development of an aptamer based lateral flow test strip for a diabetes biomarker
(University of the Western Cape, 2019)Diabetes mellitus is one of the major chronic diseases that poses a significant risk to human health globally. Current diagnostics for diabetes are based on blood glucose measurements, which can go unnoticed for years. ... -
Development of an operon detection algorithm to analyze gene regulation in drug resistant Mycobacterium tuberculosis
(University of the Western Cape, 2022)In prokaryotes, operon structures often form to allow microorganisms to respond rapidly and efficiently to changing environmental conditions. Operons are sets of neighbouring genes which are co-regulated and co-transcribed. ... -
Development of Anode Materials Using Electrochemical Atomic Layer Deposition (E-ALD) for Energy Applications
(University of the Western Cape, 2018)Nanomaterials have been found to undeniably possess superior properties than bulk structures across many fields of study including natural science, medicine, materials science, electronics etc. The study of nano-sized ... -
The development of appropriate brine electrolysers for disinfection of rural water supplies
(University of the Western Cape, 2005)A comparative study of electrolysers using different anodic materials for the electrolysis of brine (sodium chloride) for the production of sodium hypochlorite as a source of available chlorine for disinfection of rural ... -
The Development of Appropriate Brine Electrolysers for Disinfection of Rural water supplies
(University of the Western Cape, 2005)A comparative study of electrolysers using different anodic materials for the electrolysis of brine (sodium chloride) for the production of sodium hypochlorite as a source of A comparative study of electrolysers using ... -
Development of aqueous ion-intercalation battery systems for high power and bulk energy storage
(2013)Aqueous ion-intercalation batteries (AIB’s) have the potential to provide both high power for hybrid-electric transport, and low cost bulk energy storage for electric grid supply. However, a major setback to AIB development ... -
Development of capacitive deionisation electrodes: optimization of fabrication methods and composition
(University of the Western Cape, 2017)The objective of this research was to optimize the fabrication methods for and compositions of electrodes for the Membrane Capacitive Deionisation (MCDI) system. Two electrode fabrication methods were developed, namely a ... -
Development of capacitive deionisation electrodes: optimization of fabrication methods and composition
(University of the Western Cape, 2020)Membrane Capacitive Deionisation (MCDI) is a technology used to desalinate water where a potential is applied to an electrode made of carbonaceous materials resulting in ion adsorption. Processes and materials for the ... -
Development of clinical guidelines for the management of post-operative pain within the medico-socio-cultural context of Ghana
(2012)Literature on post-operative pain indicates that post-operative pain is inadequately managed in many countries including Ghana. Little was also known about post-operative pain (POP) response and management in Ghana. This ... -
Development of Copper Selenide Quantum Dots-Based Therapeutic Drug Monitoring Biosensors for Toremifene - A Breast Cancer Drug
(University of the Western Cape, 2017)With rising knowledge of the effects on plasma concentration caused by allelic variations in the cytochrome P450 genes and other metabolic factors such as drug-drug or drug-food interactions, more attention is paid to the ... -
Development of electrochemical sensors containing bimerallic silver and gold nanoparticles
(University of the Western Cape, 2010)Polyaromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants that have been shown to be teratogenic, mutagenic and carcinogenic and pose serious threats to the health of aquatic and human life. Several methods ... -
Development of electrochemical ZnSe Quantam dots biosensors for low-level detection of 17β-Estradiol estrogenic endocrine disrupting compound
(University of the Western Cape, 2010)The main thesis hub was on development of two electrochemical biosensors for the determination of 17β-estradiol-estradiol: an estrogenic endocrine disrupting compound. Endocronology have significantly shown that the endocrine ... -
The development of functionalized metallic nanoparticles for the treatment of brain cancer
(University of the Western Cape, 2019)Cancers of the nervous system often result from abnormal and uncontrolled growth of cells in nervous tissue. Glioblastoma Multiforme (GBM) and neuroblastoma (NB) are among the most common nervous system-associated cancers ... -
Development of genotyping systems for pharmacogenomics profiling
(University of the Western Cape, 2016)Genetic variability in genes encoding drug metabolizing enzymes, transporters and targets are known to be the main factors of inter-individual differences in therapeutic outcome. Genetic factors are estimated to be responsible ... -
The development of graphene oxide sheet- and polyanilino-immunosensor systems for lipoarabinomannan (LAM) tuberculosis biomarker
(University of the Western Cape, 2017)Tuberculosis (TB) is an infectious disease with adverse effect on a global scale. The disease is one of the major causes of death in sub-Saharan Africa. Nearly 70% of TB-infected persons are co-infected by the human ...