Department of Medical BioSciences: Recent submissions
Now showing items 41-60 of 231
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The prevalence, risk factors and serotypes of GBS in Libyan women at labour and the rate of vertical transmission of GBS from mother to infant
(University of the Western Cape, 2022)Group B Streptococcus (GBS) also known as Streptococcus agalactia, is one of the most important causes of serious neonatal infections. Early detection of GBS colonisation in the mother is thus of primary importance to ... -
Investigating the relationship between iron deficiency and depressive symptoms in relation to the body compositions of students residing in the Western Cape
(University of the Western Cape, 2022)Iron deficiency is the consequence of a prolonged diminished iron balance, whereby iron stores are no longer sufficient to meet the requirements of regular iron turnover. It is the most ubiquitous single nutrient deficiency, ... -
Sperm function in different human sperm subpopulations
(University of the Western Cape, 2022)Human semen contains a heterogenous population of spermatozoa of which only a certain fraction is physiologically suitable for fertilization. Functional characteristics of these subpopulations and sperm separation ... -
Investigating novel aspects of the blood-brain barrier using high resolution electron microscopy
(University of the Western Cape, 2022)The blood-brain barrier (BBB) is a restrictive interface located between the blood circulation and the central nervous system (CNS), regulating the homeostatic environment of the neuronal milieu, by controlling the ... -
The association of BMI and blood pressure measurements with depressive and quality of life scores in university students
(University of the Western Cape, 2022)Depression is a very common and serious mental illness. Studies have shown that depression has a significant impact on both social and economic aspects of sufferers worldwide as well as in South Africa. Research has shown ... -
The effects of carbon-based nanoparticle surface functionalization on immune responses
(University of the Western Cape, 2022)Nano-based technologies are highly desired for the unique properties achieved through size restrictions. Nanoparticles (NPs) achieve a higher surface-to-volume ratio during synthesis. As a result there is a greater rate ... -
The paracrine effect of normoxic and hypoxic cancer secretions on blood-brain barrier endothelial cells
(University of the Western Cape, 2022)Cancer is the most common leading cause of death worldwide. Glioblastoma and breast cancer are the most aggressive solid tumour. The survival rate of these tumours depends on their ability to progress and spread. These ... -
Tyrosol production of Candida species by plant extracts used for skin treatment remedies
(University of the Western Cape, 2022)The fungal genus Candida is a collection of approximately 150 asporogenous yeast species which are able to cause life-threatening diseases when the normal host defences have been compromised. The most commonly isolated ... -
Investigating factors that influence the breeding success of the endangered African penguin (Spheniscus demersus) at a mainland and island colony in the Western Cape, South Africa
(University of Western Cape, 2022)Since the 1950s the global seabird population have declined by 70% and today some penguin species are amongst the most threatened seabirds in the world. The African penguin (Spheniscus demersus) population experienced a ... -
A retrospective analysis of semen samples and reproductive hormones in Africa and the middle east
(University of Western Cape, 2022)Semen analysis is the cornerstone for the investigation of male infertility. Semen quality can be influenced by geographical location, age, ejaculatory abstinence, and season. In 2010, the WHO published criteria for human ... -
Investigating novel aspects of the blood-brain barrier using high resolution electron microscopy
(University of the Western Cape, 2022)The blood-brain barrier (BBB) is a restrictive interface located between the blood circulation and the central nervous system (CNS), regulating the homeostatic environment of the neuronal milieu, by controlling the ... -
The screening of phyto-pesticides for potential adverse effects on human health
(University of the Western Cape, 2010)Pesticides are designed to control or eliminate pests such as insects, rodents, weeds, bacteria, and fungi. They are used at a global scale for agricultural produce. Although pesticides playa significant role in increasing ... -
The impact of nanoparticles on the proteome of cultured human cells
(2021)Living organisms are constantly being exposed to nanoparticles (NPs) in the environment via air, water, soil. Routes of exposure are usually in the form of industrial, occupational exposure, as well as therapeutic ... -
Evaluating cape honey bee sperm quality and the in vitro effect of miticides on sperm functionality and structure
(University of Western Cape, 2021)Apis mellifera (honey bees) are essential pollinators and thus considered a keystone species. Reproductive success is therefore important to the survival of the species, with drone sperm quality playing a vital role in ... -
Investigating hypoglycaemic effects and safety of the herbal product – jt2016 in vivo study
(University of the Western Cape, 2021)Diabetes has since been a global epidemic; an estimated 5.0 million deaths of diabetes in the world have been recorded; one in 11 adults have diabetes (415 million); and by 2040, one adult in 10 (642 million) will have ... -
Investigating hypoglycaemic effects and safety of the herbal Product – JT2016 in vivo study
(University of the Western Cape, 2021)Diabetes has since been a global epidemic; an estimated 5.0 million deaths of diabetes in the world have been recorded; one in 11 adults have diabetes (415 million); and by 2040, one adult in 10 (642 million) will have ... -
The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro
(University of Western Cape, 2021)The testes play a central role in the male reproductive system, as they represent the sites of male sex steroidogenesis and of spermatogenesis. Leydig cells, located at the testicular interstitium, produce predominantly ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
(University of Western Cape, 2021)Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ... -
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS remains one of the major causes of death in the world and mostly in sub-Saharan Africa. To date, neither ... -
Epidemiological study of Tuberculosis in Macassar camp
(University of the Western Cape, 1995)The aim of this study was to determine and evaluate the prevalence of TB infection, active TB cases and the risk factors associated with TB infection in Macassar Camp in Macassar (about 40 km from Cape Town on the False ...