Magister Scientiae - MSc (Medical BioSciences)
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Recent Submissions
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The effects of doxorubicin loaded chitosan-alginate nanoparticles on SK-N-BE(2) neuroblastoma cells
(University of the Western Cape, 2022)Cancer is a life-threatening disease and one of the leading causes of death globally. Cancer was thought to be associated with developed countries only but it is increasingly becoming a major health challenge in developing ... -
An electrophysiological exploration into the Sertoli cell, utilizing plant extracts with a view to contraception
(University of the western cape, 2003)Certa in medicinal plant extracts have been shown to have a contraceptive effect on male rats (Rajasekaran et al. , 1988) and mice (Kong et al., 1986). A possible site for the mechanism of action has been identified as the ... -
The influence of maternal nicotine exposure on neonatal lung development: An enzymatic and metabolic study
(University of the Western Cape, 1999)Chapter I, the literature review, gives the reader a sound background knowledge of the following: normal lung structural development in humans and rats, metabolic development with reference to structural development, tobacco ... -
The effects of Exomis micriphylla and Atriplex lindleyi on metabolism and health
(University of the Western Cape, 2002)For many decades people have used plants for healing various ailments. Plant products have been used in herbal remedies especially for their anti-infective properties. The following study was undertaken to assess the ... -
Tumour suppression and subdual of cancer (tussc) in elephants: An in vitro study to shed light on Peto’s paradox
(University of the Western Cape, 2022)Logic would suggest that cancer incidence is related to body mass and longevity. Gigantic animals such as elephants with a longer lifespan (more lifetime of cell divisions) and a larger body size (more cells) will have ... -
Structural and functional aspects of sperm after transit through the fallopian tube of the sheep
(University of the Western Cape, 1996)Ejaculated mammalian spermatozoa have the potential for fertilization. The acquisition of the ability to fertilize a fully invested oocyte occurs during the passage through the female reproductive tract. These post-ejaculatory ... -
The influence of maternal nicotine exposure on development lung as gas exchanger: the protective effect of copper
(University of the Western Cape, 1998)The influence of tobacco smoking on the developing fetus is well reported. Maternal nicotine exposure during pregnancy and lactation interferes with fetal and neonatal lung growth and development, rendering the lungs more ... -
The antioxidant properties of melatonin during chemical hypoxia and reoxygenation injury in rat ventricular myocytes
(University of the Western Cape, 2000)It is well known that ischaemia chemical hypoxia followed by reperfusion is not always accompanied by recovery of myocardial function and often produces further cell damage (Hearse et al., 1973). This phenomenon commonly ... -
The influence of maternal nicotine exposure on neonatal rat lung septal status
(University of the Western Cape, 1995)The aim of this study was to determine the effect of maternal nicotine exposure on the status of rat lung alveolar septa of 1 to 2l day old offspring. Wistar dams were injected subcutaneously, using a dosage of 1 mg ... -
Ecology and conservation of high altitude amphibians
(UWC, 2002)This study looked at the breeding ecology of the anurans, found in the Landdroskop mountain range in Grabouw, and some recommendations as to their conservation are made. There is very little known about the frogs in South ... -
Circadian activity rhythms and early gene expression in the suprachiasmatic nucleus of a diurnal rodent, Rhabdomys pumilio
(UWC, 2001)Although humans are diurnal in behavior, animal models used for the study of circadian rhythms are mainly restricted to nocturnal rodents. This study focused on circadian behavior and gene expression in a diurnal rodent ... -
Student experiences of life science practicals
(UWC, 2001)Science Educationists seem to agree that practical work should form an important component of any science course. Many students arrive at University without having been exposed to any practical work, while others were ... -
The influence of maternal nicotine exposure on neonatal lung development : an enzymatic and metabolic study
(UWC, 1999)Chapter I, the literature review, gives the reader a sound background knowledge of the following: normal lung structural development in humans and rats, metabolic development with reference to structural development, tobacco ... -
The effects of Elytropappus rhinocerotis Cass and Pelargonium triste (L.) L'Hèrit on animal health and metabolism
(University of the Western Cape, 2003)Many South Africans use cultural traditions and practices in the management of their health. Elytropappus rhinocerotis is an important medicinal plant, which is widely distributed in regions of South Africa. The objective ... -
Microscopic analysis of In vitro and In vivo effects of functionalized gold nanoparticles on the liver, kidney, spleen, heart and pancreas of male wistar rats
(University of the Western Cape, 2022)Nanotechnology represents a promising knowledge based platform that can solve human needs and ailments, especially in cases like cancers, diabetes, antibiotic drug resistances etc. Many metallic nanoparticles are being ... -
The effect of Nicotine exposure on aspects of liver Carbohydrate metabolism
(University of the Western Cape, 1989)The liver plays an important role in maintaining the blood glucose concentration. In this respect glycogenolysis and gluconeogenesis play an important role. Interference with these pathways may therefore have an effect on ... -
Aspects of the reproductive physiology of male vervet monkeys maintained in a laboratory environment
(University of the Western Cape, 1995)In biomedical research limited use has been made internationally of African non-human primates. As a result, their reproductive physiology has been less well defined, when compared to the more commonly used macaque species. ... -
An evaluation of the biopesticidal characteristics of Hetichrysum marifolium and Helichrysum patulum and their effects on animal metabolism
(University of the Western Cape, 2002)There ate a number of pesticides that are suspected to be endocrine disrupters' Many of these pesticides are man-made. Endocrine disrupters are chemicals that can lead to an increase in birth defects, sexual abnormalities, ... -
An assessment of carpobrotrn actnacifurmis and cissampelos capensis as potential antimicrobial agents and their effects on animal metabolism
(University of the Western Cape, 2002)An assessm entof Carpobrotus acinaciformib and Cissampelos capensis as potential antimicrobialagentsandtheireffectsonanimalmetabolism -
Nanostructured immunosensor for low level detection of waterborne cryptosporidium
(University of the Western Cape, 2022)A major causative agent of gastrointestinal disease is Cryptosporidium, a protozoan waterborne parasite identified in over 70 countries. Cryptosporidium infection is a cause of high disease morbidity in children and the ...