Browsing Magister Scientiae - MSc (Bioinformatics) by Author "Tiffin, Nicki"
Now showing items 1-3 of 3
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A computational characterisation of the relationship between genome structure and disease genes
Kibler, Tracey Deborah (University of the Western Cape, 2012)This is a pilot study to investigate the relationship between disease gene status and the structure of the human genome with specific reference to regions of recombination. It compares certain characteristics of a control ... -
Integrating regulatory and methylome data for the discovery of clear cell Renal Cell Carcinoma (ccRCC) variants
Calvert-Joshua, Tracey (University of the Western Cape, 2015)Kidney cancers, of which clear cell renal cell carcinoma comprises an estimated 70%, have been placed amongst the top ten most common cancers in both males and females. With a mortality rate that exceeds 40%, kidney cancer ... -
“An investigation into the MicroRNA-gene interactions involved in the pathogenesis of systemic lupus erythematosus”
Pitts, Stephanie Julia (University of the Western Cape, 2015)Systemic lupus erythematosus is a chronic, inflammatory disease characterised by the production of autoantibodies which target particularly the nuclear components of multiple cell types throughout the body. MicroRNA’s have ...