Browsing Magister Scientiae - MSc (Bioinformatics) by Subject "Antiretroviral drugs"
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Molecular dynamic simulation studies of the South African HIV-1 Integrase subtype C protein to understand the structural impact of naturally occurring polymorphisms
(University of Western Cape, 2021)The viral Integrase (IN) protein is an essential enzyme of all known retroviruses, including HIV-1. It is responsible for the insertion of viral DNA into the human genome. It is known that HIV-1 is highly diverse with a ...