Browsing Philosophiae Doctor - PhD (Medical BioScience) by Author "Dept. of Medical BioSciences"
Now showing items 1-12 of 12
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Apoptotic markers in ejaculated human spermatozoa
Brooks, Nicole Lisa (University of the Western Cape, 2005)The role of male germ cell death in spermatogenesis is an important one as it removes dysfunctional or genetically damaged germ cells and is necessary to maintain an optimal germ cell to Sertoli cell ratio. The formation ... -
Assessment of the biological quality of raw and treated effluents from three sewage treatment plants in the Western Cape, South Africa
Hendricks, Rahzia (University of the Western Cape, 2011)The aim of this study was to compare the water quality of raw wastewater and treated sewage effluents from three different sewage treatment plants in the Western Cape, South Africa. The treatment plants investigated are ... -
Effect of tea and herbal infusions on mammalian reproduction and fertility
Opuwari, Chinyerum Sylvia (University of the Western Cape, 2013)Camellia sinensis (tea) and Aspalathus linearis (rooibos) may improve reproductive function owing to their antioxidant properties. To test this hypothesis, male and female rats were given 2% and 5% green tea (Gt), black ... -
The effects of artificial and natural sweeteners on various physiological systems
Rahiman, Farzana (University of the Western Cape, 2011)This study aimed to investigate the effects of commercially available natural (sugar cane molasses, white sugar and brown sugar) and artificial (Canderel, Equal, Natreen, Sweetex, Splenda and Swheet) sweeteners on various ... -
Fatty acids as cancer preventive tools in the dietary modulation of altered lipid profiles associated with hepatocarcinogenesis
Abel, Stefan (University of the Western Cape, 2005)This thesis consists of a brief description on cancer, carcinogenesis, the changes in the type and level of dietary fat available in our diets over time and association with the development of certain diseases. The main ... -
The implementation of in vitro assays to screen environmental samples for male reproductive toxicity
Ebrahim, Mozaffar (University of the Western Cape, 2010)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals which interfere with, or have adverse effects on the production, distribution and function of natural hormones, thereby affecting normal endocrine ... -
The influence of maternal nicotine exposure on selected glycolytic and cytochrome P450 enzymes in developing neonatal rat lung
Gamieldien, Kareemah (University of the Western Cape, 2005)The structural and functional integrity of a developing and maturing fetal and neonatal lung is critically dependent on carbohydrate metabolism. The energy derived from carbohydrate metabolism is utilized during the processed ... -
An investigation into the effect of maternal exposure to nicotine and copper on neonatal lung development
Windvogel, Shantal Lynn (University of the Western Cape, 2006)In the 20th century, where tobacco smoking continues to be the leading preventable cause of death, an alarming number of people continue to smoke, despite awareness of the implications of exposure for themselves and those ... -
Premature aging of the lungs of the offspring induced by maternal nicotine exposure during gestation and lactation: protective effects of tomato juice
Mutemwa, Muyunda (University of the Western Cape, 2012)exposed to nicotine through the blood and the milk of the mother. Nicotine is thus expected to interact with the developing fetus and the offspring of mothers who smoke or use NRT for smoking cessation, resulting in the ... -
The screening of phyto-pesticides for potential adverse effects on human health
Shoko, Yeukai Phoebe (University of the Western Cape, 2010)Pesticides are designed to control or eliminate pests such as insects, rodents, weeds, bacteria, and fungi. They are used at a global scale for agricultural produce. Although pesticides play a significant role in increasing ... -
Sperm mitochondria: species specificity and relationships to sperm morphometric features and sperm function in selected mammalian species
Maree, Liana (University of the Western Cape, 2011)Numerous studies on mammalian spermatozoa have reported large variations in the dimensions of the main sperm structural components, namely the head, midpiece and flagellum. These variations in sperm architecture are believed ... -
Synergistic effects of mixtures of fungicides and medicinal plant extracts against Botrytis cinerea
Vries, Filicity Ann (University of the Western Cape, 2008)We hypothesize that South African medicinal plants contain compounds that can act in synergism with synthetic antifungal compounds. Four fungicides - Sporekill™, Rovral™, Terminator™ and Teldor™ at doses 0.1, 0.2, 0.4 and ...