Browsing Philosophiae Doctor - PhD (Medical BioScience) by Author "Ekpo, Okobi"
Now showing items 1-4 of 4
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The development of targeting nanosystems for the treatment of glioblastoma and neuroblastoma tumours
Boltman, Taahirah (University of the Western Cape, 2022)Chlorotoxin (CTX) peptide selectively targets glioblastoma multiforme (GB) and neuroblastoma (NB) and has excellent blood-brain barrier permeability. Therefore, CTX is a promising targeting molecule for nanoparticle (NP) ... -
An evaluation of cancer biomarkers in normal ovarian epithelial cells and ovarian cancer cell lines
Fruka, Tayra (University of the Western Cape, 2019)Introduction: Globally, there are over 190,000 new reported cases of ovarian cancers per annum. This comprises 3% to 4% of all cancers in women. Ovarian cancer is one of the leading causes of deaths in women. Ovarian cancer ... -
Investigating the anti-cancer activity of novel phenothiazines in glioblastoma
Omoruyi, Sylvester Ifeanyi (University of the Western Cape, 2018)Glioblastoma multiforme (GBM) remains the most malignant of all primary adult brain tumours. It is a highly invasive and vascularized neoplasm with limited treatment options and very low survival rate. GBM tumours are ... -
Role of Rutin in 1-Mtthyl-4-Phenylpyridinium toxicity: Therapeutic implications for Parkinson's disease
Enogieru, Adaze Bijou (University of the Western Cape, 2018)Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. Although the etiology of PD is not ...